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Keywords:

  • inherited platelet disorders;
  • platelet glycoproteins;
  • thrombocytopenia;
  • platelet receptors;
  • platelet bleeding

Summary

The inherited platelet disorders are an uncommon cause of symptomatic bleeding. They may be difficult to diagnose (and are likely to be under-diagnosed) and pose problems in management. This review discusses the inherited platelet disorders summarising the current state of the art with respect to investigation and diagnosis and suggests how to manage bleeding manifestations with particular attention to surgical interventions and the management of pregnancy.