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  • Altuvia, Y., Landgraf, P., Lithwick, G., Elefant, N., Pfeffer, S., Aravin, A., Brownstein, M.J., Tuschl, T. & Margalit, H. (2005) Clustering and conservation patterns of human microRNAs. Nucleic Acids Research, 33, 26972706.
  • Bentwich, I., Avniel, A., Karov, Y., Aharonov, R., Gilad, S., Barad, O., Barzilai, A., Einat, P., Einav, U., Meiri, E., Sharon, E., Spector, Y. & Bentwich, Z. (2005) Identification of hundreds of conserved and nonconserved human microRNAs. Nature Genetics, 37, 766770.
  • Berezikov, E., Guryev, V., Van De Belt, J., Wienholds, E., Plasterk, R.H. & Cuppen, E. (2005) Phylogenetic shadowing and computational identification of human microRNA genes. Cell, 120, 2124.
  • Van Den Berg, A., Kroesen, B.J., Kooistra, K., De Jong, D., Briggs, J., Blokzijl, T., Jacobs, S., Kluiver, J., Diepstra, A., Maggio, E. & Poppema, S. (2003) High expression of B-cell receptor inducible gene BIC in all subtypes of Hodgkin lymphoma. Genes, Chromosomes & Cancer, 37, 2028.
  • Bernstein, E., Kim, S.Y., Carmell, M.A., Murchison, E.P., Alcorn, H., Li, M.Z., Mills, A.A., Elledge, S.J., Anderson, K.V. & Hannon, G.J. (2003) Dicer is essential for mouse development. Nature Genetics, 35, 215217.
  • Bottoni, A., Piccin, D., Tagliati, F., Luchin, A., Zatelli, M.C. & Degli Uberti, E.C. (2005) miR-15a and miR-16-1 down-regulation in pituitary adenomas. Journal of Cellular Physiology, 204, 280285.
  • Calin, G.A. & Croce, C.M. (2006) MicroRNA-cancer connection: the beginning of a new tale. Cancer Research, 66, 73907394.
  • Calin, G.A., Dumitru, C.D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K., Rassenti, L., Kipps, T., Negrini, M., Bullrich, F. & Croce, C.M. (2002) Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America, 99, 1552415529.
  • Calin, G.A., Sevignani, C., Dumitru, C.D., Hyslop, T., Noch, E., Yendamuri, S., Shimizu, M., Rattan, S., Bullrich, F., Negrini, M. & Croce, C.M. (2004a) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proceedings of the National Academy of Sciences of the United States of America, 101, 29993004.
  • Calin, G.A., Liu, C.G., Sevignani, C., Ferracin, M., Felli, N., Dumitru, C.D., Shimizu, M., Cimmino, A., Zupo, S., Dono, M., Dell'Aquila, M.L., Alder, H., Rassenti, L., Kipps, T.J., Bullrich, F., Negrini, M. & Croce, C.M. (2004b) MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proceedings of the National Academy of Sciences of the United States of America, 101, 1175511760.
  • Calin, G.A., Ferracin, M., Cimmino, A., Di Leva, G., Shimizu, M., Wojcik, S.E., Iorio, M.V., Visone, R., Sever, N.I., Fabbri, M., Iuliano, R., Palumbo, T., Pichiorri, F., Roldo, C., Garzon, R., Sevignani, C., Rassenti, L., Alder, H., Volinia, S., Liu, C.G., Kipps, T.J., Negrini, M. & Croce, C.M. (2005) A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. New England Journal of Medicine, 353, 17931801.
  • Chan, J.A., Krichevsky, A.M. & Kosik, K.S. (2005) MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Research, 65, 60296033.
  • Chen, C.Z., Li, L., Lodish, H.F. & Bartel, D.P. (2004) MicroRNAs modulate hematopoietic lineage differentiation. Science, 303, 8386.
  • Ciafre, S.A., Galardi, S., Mangiola, A., Ferracin, M., Liu, C.G., Sabatino, G., Negrini, M., Maira, G., Croce, C.M. & Farace, M.G. (2005) Extensive modulation of a set of microRNAs in primary glioblastoma. Biochemical and Biophysical Research Communications, 334, 13511358.
  • Cimmino, A., Calin, G.A., Fabbri, M., Iorio, M.V., Ferracin, M., Shimizu, M., Wojcik, S.E., Aqeilan, R.I., Zupo, S., Dono, M., Rassenti, L., Alder, H., Volinia, S., Liu, C.G., Kipps, T.J., Negrini, M. & Croce, C.M. (2005) miR-15 and miR-16 induce apoptosis by targeting BCL2. Proceedings of the National Academy of Sciences of the United States of America, 102, 1394413949.
  • Clurman, B.E. & Hayward, W.S. (1989) Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: evidence for stage-specific events. Molecular and Cellular Biology, 9, 26572664.
  • Cobb, B.S., Nesterova, T.B., Thompson, E., Hertweck, A., O'Connor, E., Godwin, J., Wilson, C.B., Brockdorff, N., Fisher, A.G., Smale, S.T. & Merkenschlager, M. (2005) T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer. Journal of Experimental Medicine, 201, 13671373.
  • Costinean, S., Zanesi, N., Pekarsky, Y., Tili, E., Volinia, S., Heerema, N. & Croce, C.M. (2006) Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice. Proceedings of the National Academy of Sciences of the United States of America, 103, 70247029.
  • Eis, P.S., Tam, W., Sun, L., Chadburn, A., Li, Z., Gomez, M.F., Lund, E. & Dahlberg, J.E. (2005) Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proceedings of the National Academy of Sciences of the United States of America, 102, 36273632.
  • Fazi, F., Rosa, A., Fatica, A., Gelmetti, V., De Marchis, M.L., Nervi, C. & Bozzoni, I. (2005) A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell, 123, 819831.
  • Felli, N., Fontana, L., Pelosi, E., Botta, R., Bonci, D., Facchiano, F., Liuzzi, F., Lulli, V., Morsilli, O., Santoro, S., Valtieri, M., Calin, G.A., Liu, C.G., Sorrentino, A., Croce, C.M. & Peschle, C. (2005) MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proceedings of the National Academy of Sciences of the United States of America, 102, 1808118086.
  • Garzon, R., Pichiorri, F., Palumbo, T., Iuliano, R., Cimmino, A., Aqeilan, R., Volinia, S., Bhatt, D., Alder, H., Marcucci, G., Calin, G.A., Liu, C.G., Bloomfield, C.D., Andreeff, M. & Croce, C.M. (2006) MicroRNA fingerprints during human megakaryocytopoiesis. Proceedings of the National Academy of Sciences of the United States of America, 103, 50785083.
  • Garzon, R., Pichiorri, F., Palumbo, T., Visentini, M., Aqeilan, R., Cimmino, A., Wang, H., Sun, H., Volinia, S., Alder, H., Calin, G.A., Liu, C.G., Andreeff, M. & Croce, C.M. (2007) MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia. Oncogene, doi:10.1038/sj.onc.1210186.
  • Gauwerky, C.E., Huebner, K., Isobe, M., Nowell, P.C. & Croce, C.M. (1989) Activation of MYC in a masked t(8;17) translocation results in an aggressive B-cell leukemia. Proceedings of the National Academy of Sciences of the United States of America, 86, 88678871.
  • Georgantas, III, R.W., Hildreth, R., Morisot, S., Alder, J., Liu, C.G., Heimfeld, S., Calin, G.A., Croce, C.M. & Civin, C.I. (2007) CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control. Proceedings of the National Academy of Sciences of the United States of America, 104, 27502755.
  • Griffiths-Jones, S., Grocock, R.J., Van Dongen, S., Bateman, A. & Enright, A.J. (2006) miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Research, 34, D140D144.
  • Hayashita, Y., Osada, H., Tatematsu, Y., Yamada, H., Yanagisawa, K., Tomida, S., Yatabe, Y., Kawahara, K., Sekido, Y. & Takahashi, T. (2005) A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Research, 65, 96289632.
  • He, L., Thomson, J.M., Hemann, M.T., Hernando-Monge, E., Mu, D., Goodson, S., Powers, S., Cordon-Cardo, C., Lowe, S.W., Hannon, G.J. & Hammond, S.M. (2005) A microRNA polycistron as a potential human oncogene. Nature, 435, 828833.
  • Hertel, J., Lindemeyer, M., Missal, K., Fried, C., Tanzer, A., Flamm, C., Hofacker, I.L. & Stadler, P.F. (2006) The expansion of the metazoan microRNA repertoire. BMC Genomics, 7, 25.
  • Iorio, M.V., Ferracin, M., Liu, C.G., Veronese, A., Spizzo, R., Sabbioni, S., Magri, E., Pedriali, M., Fabbri, M., Campiglio, M., Menard, S., Palazzo, J.P., Rosenberg, A., Musiani, P., Volinia, S., Nenci, I., Calin, G.A., Querzoli, P., Negrini, M. & Croce, C.M. (2005) MicroRNA gene expression deregulation in human breast cancer. Cancer Research, 65, 70657070.
  • Jiang, J., Lee, E.J. & Schmittgen, T.D. (2006) Increased expression of microRNA-155 in Epstein-Barr virus transformed lymphoblastoid cell lines. Genes, Chromosomes & Cancer, 45, 103106.
  • John, B., Enright, A.J., Aravin, A., Tuschl, T., Sander, C. & Marks, D.S. (2004) Human MicroRNA targets. PLoS Biology, 2, e363.
  • Kanellopoulou, C., Muljo, S.A., Kung, A.L., Ganesan, S., Drapkin, R., Jenuwein, T., Livingston, D.M. & Rajewsky, K. (2005) Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes & Development, 19, 489501.
  • Karnan, S., Tagawa, H., Suzuki, R., Suguro, M., Yamaguchi, M., Okamoto, M., Morishima, Y., Nakamura, S. & Seto, M. (2004) Analysis of chromosomal imbalances in de novo CD5-positive diffuse large-B-cell lymphoma detected by comparative genomic hybridization. Genes, Chromosomes & Cancer, 39, 7781.
  • Khvorova, A., Reynolds, A. & Jayasena, S.D. (2003) Functional siRNAs and miRNAs exhibit strand bias. Cell, 115, 209216.
  • Kim, V.N. (2005) MicroRNA biogenesis: coordinated cropping and dicing. Nature Reviews. Molecular Cell Biology, 6, 376385.
  • Kluiver, J., Poppema, S., De Jong, D., Blokzijl, T., Harms, G., Jacobs, S., Kroesen, B.J. & Van Den Berg, A. (2005) BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas. Journal of Pathology, 207, 243249.
  • Kluiver, J., Haralambieva, E., De Jong, D., Blokzijl, T., Jacobs, S., Kroesen, B.J., Poppema, S. & Van Den Berg, A. (2006a) Lack of BIC and microRNA miR-155 expression in primary cases of Burkitt lymphoma. Genes, Chromosomes & Cancer, 45, 147153.
  • Kluiver, J., Van Den Berg, A., De Jong, D., Blokzijl, T., Harms, G., Bouwman, E., Jacobs, S., Poppema, S. & Kroesen, B.J. (2006b) Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma. Oncogene, doi:10.1038/sj.onc.1210147.
  • Krek, A., Grun, D., Poy, M.N., Wolf, R., Rosenberg, L., Epstein, E.J., MacMenamin, P., Da Piedade, I., Gunsalus, K.C., Stoffel, M. & Rajewsky, N. (2005) Combinatorial microRNA target predictions. Nature Genetics, 37, 495500.
  • Lee, R.C. & Ambros, V. (2001) An extensive class of small RNAs in Caenorhabditis elegans. Science, 294, 862864.
  • Lee, R.C., Feinbaum, R.L. & Ambros, V. (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 75, 843854.
  • Lee, Y., Hur, I., Park, S.Y., Kim, Y.K., Suh, M.R. & Kim, V.N. (2006) The role of PACT in the RNA silencing pathway. EMBO Journal, 25, 522532.
  • Lewis, B.P., Shih, I.H., Jones-Rhoades, M.W., Bartel, D.P. & Burge, C.B. (2003) Prediction of mammalian microRNA targets. Cell, 115, 787798.
  • Lewis, B.P., Burge, C.B. & Bartel, D.P. (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 120, 1520.
  • Lim, L.P., Lau, N.C., Garrett-Engele, P., Grimson, A., Schelter, J.M., Castle, J., Bartel, D.P., Linsley, P.S. & Johnson, J.M. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature, 433, 769773.
  • Lin, S.L., Chang, S.J. & Ying, S.Y. (2006) First in vivo evidence of microRNA-induced fragile X mental retardation syndrome. Molecular Psychiatry, 11, 616617.
  • Linsley, P.S., Schelter, J., Burchard, J., Kibukawa, M., Martin, M.M., Bartz, S.R., Johnson, J.M., Cummins, J.M., Raymond, C.K., Dai, H., Chau, N., Cleary, M., Jackson, A.L., Carleton, M. & Lim, L. (2007) Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Molecular and Cellular Biology, 27, 22402252.
  • Liu, J., Valencia-Sanchez, M.A., Hannon, G.J. & Parker, R. (2005) MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nature Cell Biology, 7, 719723.
  • Lu, J., Getz, G., Miska, E.A., Alvarez-Saavedra, E., Lamb, J., Peck, D., Sweet-Cordero, A., Ebert, B.L., Mak, R.H., Ferrando, A.A., Downing, J.R., Jacks, T., Horvitz, H.R. & Golub, T.R. (2005) MicroRNA expression profiles classify human cancers. Nature, 435, 834838.
  • Martin, M.M., Lee, E.J., Buckenberger, J.A., Schmittgen, T.D. & Elton, T.S. (2006) MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts. Journal of Biological Chemistry, 281, 1827718284.
  • Mathas, S., Hinz, M., Anagnostopoulos, I., Krappmann, D., Lietz, A., Jundt, F., Bommert, K., Mechta-Grigoriou, F., Stein, H., Dorken, B. & Scheidereit, C. (2002) Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. EMBO Journal, 21, 41044113.
  • Metzler, M., Wilda, M., Busch, K., Viehmann, S. & Borkhardt, A. (2004) High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes, Chromosomes & Cancer, 39, 167169.
  • Monticelli, S., Ansel, K.M., Xiao, C., Socci, N.D., Krichevsky, A.M., Thai, T.H., Rajewsky, N., Marks, D.S., Sander, C., Rajewsky, K., Rao, A. & Kosik, K.S. (2005) MicroRNA profiling of the murine hematopoietic system. Genome Biology, 6, R71.
  • Muljo, S.A., Ansel, K.M., Kanellopoulou, C., Livingston, D.M., Rao, A. & Rajewsky, K. (2005) Aberrant T cell differentiation in the absence of Dicer. Journal of Experimental Medicine, 202, 261269.
  • Naguibneva, I., Ameyar-Zazoua, M., Polesskaya, A., Ait-Si-Ali, S., Groisman, R., Souidi, M., Cuvellier, S. & Harel-Bellan, A. (2006) The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation. Nature Cell Biology, 8, 278284.
  • O'Connell, R.M., Taganov, K.D., Boldin, M.P., Cheng, G. & Baltimore, D. (2007) MicroRNA-155 is induced during the macrophage inflammatory response. Proceedings of the National Academy of Sciences of the United States of America, 104, 16041609.
  • O'Donnell, K.A., Wentzel, E.A., Zeller, K.I., Dang, C.V. & Mendell, J.T. (2005) c-Myc-regulated microRNAs modulate E2F1 expression. Nature, 435, 839843.
  • Olsen, P.H. & Ambros, V. (1999) The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Developmental Biology, 216, 671680.
  • Ota, A., Tagawa, H., Karnan, S., Tsuzuki, S., Karpas, A., Kira, S., Yoshida, Y. & Seto, M. (2004) Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Research, 64, 30873095.
  • Pasquinelli, A.E., Reinhart, B.J., Slack, F., Martindale, M.Q., Kuroda, M.I., Maller, B., Hayward, D.C., Ball, E.E., Degnan, B., Muller, P., Spring, J., Srinivasan, A., Fishman, M., Finnerty, J., Corbo, J., Levine, M., Leahy, P., Davidson, E. & Ruvkun, G. (2000) Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature, 408, 8689.
  • Pekarsky, Y., Santanam, U., Cimmino, A., Palamarchuk, A., Efanov, A., Maximov, V., Volinia, S., Alder, H., Liu, C.G., Rassenti, L., Calin, G.A., Hagan, J.P., Kipps, T. & Croce, C.M. (2006) Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Research, 66, 1159011593.
  • Pfeifer, D., Pantic, M., Skatulla, I., Rawluk, J., Kreutz, C., Martens, U.M., Fisch, P., Timmer, J. & Veelken, H. (2007) Genome-wide analysis of DNA copy number changes and LOH in CLL using high-density SNP arrays. Blood, 109, 12021210.
  • Pillai, R.S., Bhattacharyya, S.N., Artus, C.G., Zoller, T., Cougot, N., Basyuk, E., Bertrand, E. & Filipowicz, W. (2005) Inhibition of translational initiation by Let-7 MicroRNA in human cells. Science, 309, 15731576.
  • Ramkissoon, S.H., Mainwaring, L.A., Ogasawara, Y., Keyvanfar, K., Philip McCoy, Jr, J., Sloand, E.M., Kajigaya, S. & Young, N.S. (2005) Hematopoietic-specific microRNA expression in human cells. Leukemia Research, 30, 643647.
  • Reinhart, B.J., Slack, F.J., Basson, M., Pasquinelli, A.E., Bettinger, J.C., Rougvie, A.E., Horvitz, H.R. & Ruvkun, G. (2000) The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature, 403, 901906.
  • Rodriguez, A., Griffiths-Jones, S., Ashurst, J.L. & Bradley, A. (2004) Identification of mammalian microRNA host genes and transcription units. Genome Research, 14, 19021910.
  • Roldo, C., Missiaglia, E., Hagan, J.P., Falconi, M., Capelli, P., Bersani, S., Calin, G.A., Volinia, S., Liu, C.G., Scarpa, A. & Croce, C.M. (2006) MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. Journal of Clinical Oncology, 24, 46774684.
  • Van Rooij, E., Sutherland, L.B., Liu, N., Williams, A.H., McAnally, J., Gerard, R.D., Richardson, J.A. & Olson, E.N. (2006) A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proceedings of the National Academy of Sciences of the United States of America, 103, 1825518260.
  • Schwarz, D.S., Hutvagner, G., Du, T., Xu, Z., Aronin, N. & Zamore, P.D. (2003) Asymmetry in the assembly of the RNAi enzyme complex. Cell, 115, 199208.
  • Sen, G.L. & Blau, H.M. (2005) Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nature Cell Biology, 7, 633636.
  • Si, M.L., Zhu, S., Wu, H., Lu, Z., Wu, F. & Mo, Y.Y. (2006) miR-21-mediated tumor growth. Oncogene, doi:10.1038/sj.onc.1210083.
  • Sonoki, T., Iwanaga, E., Mitsuya, H. & Asou, N. (2005) Insertion of microRNA-125b-1, a human homologue of lin-4, into a rearranged immunoglobulin heavy chain gene locus in a patient with precursor B-cell acute lymphoblastic leukemia. Leukemia, 19, 20092010.
  • Tam, W., Ben-Yehuda, D. & Hayward, W.S. (1997) Bic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNA. Molecular and Cellular Biology, 17, 14901502.
  • Volinia, S., Calin, G.A., Liu, C.G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., Prueitt, R.L., Yanaihara, N., Lanza, G., Scarpa, A., Vecchione, A., Negrini, M., Harris, C.C. & Croce, C.M. (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proceedings of the National Academy of Sciences of the United States of America, 103, 22572261.
  • Wightman, B., Ha, I. & Ruvkun, G. (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell, 75, 855862.
  • Woods, K., Thomson, J.M. & Hammond, S.M. (2007) Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. Journal of Biological Chemistry, 282, 21302134.
  • Yekta, S., Shih, I.H. & Bartel, D.P. (2004) MicroRNA-directed cleavage of HOXB8 mRNA. Science, 304, 594596.
  • Yeom, K.H., Lee, Y., Han, J., Suh, M.R. & Kim, V.N. (2006) Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing. Nucleic Acids Research, 34, 46224629.
  • Zeng, Y. (2006) Principles of micro-RNA production and maturation. Oncogene, 25, 61566162.
  • Zhang, L., Huang, J., Yang, N., Greshock, J., Megraw, M.S., Giannakakis, A., Liang, S., Naylor, T.L., Barchetti, A., Ward, M.R., Yao, G., Medina, A., O'Brien-Jenkins, A., Katsaros, D., Hatzigeorgiou, A., Gimotty, P.A., Weber, B.L. & Coukos, G. (2006) MicroRNAs exhibit high frequency genomic alterations in human cancer. Proceedings of the National Academy of Sciences of the United States of America, 103, 91369141.
  • Zheng, Y., Josefowicz, S.Z., Kas, A., Chu, T.T., Gavin, M.A. & Rudensky, A.Y. (2007) Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature, 445, 936940.