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  • Ballem, P.J., Segal, G.M., Stratton, J.R., Gernsheimer, T., Adamson, J.W. & Slichter, S.J. (1987) Mechanisms of thrombocytopenia in chronic autoimmune thrombocytopenic purpura. Evidence of both impaired platelet production and increased platelet clearance. The Journal of Clinical Investigation, 80, 3340.
  • Benedetti, F., De Sabata, D. & Perona, G. (1994) T suppressor activated lymphocytes (CD8+/DR+) inhibit megakaryocyte progenitor cell differentiation in a case of acquired amegakaryocytic thrombocytopenic purpura. Stem Cells, 12, 205213.
  • Chang, M., Nakagawa, P.A., Williams, S.A., Schwartz, M.R., Imfeld, K.L., Buzby, J.S. & Nugent, D.J. (2003) Immune thrombocytopenic purpura (ITP) plasma and purified ITP monoclonal autoantibodies inhibit megakaryocytopoiesis in vitro. Blood, 102, 887895.
  • Cines, D.B. & Blanchette, V.S. (2002) Immune thrombocytopenic purpura. New England Journal of Medicine, 346, 9951008.
  • Clarke, M.C., Savill, J., Jones, D.B., Noble, B.S. & Brown, S.B. (2003) Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death. The Journal of Cell Biology, 160, 577587.
  • Coppola, S., Narciso, L., Feccia, T., Bonci, D., Calabro, L., Morsilli, O., Gabbianelli, M., Maria, R.D., Testa, U. & Peschle, C. (2006) Enforced expression of KDR receptor promotes proliferation, survival and megakaryocytic differentiation of TF1 progenitor cell line. Cell Death and Differentiation, 13, 6174.
  • Dameshek, W. & Miller, E.B. (1946) The megakaryocytes in idiopathic thrombocytopenic purpura, a form of hypersplenism. Blood , 1, 2752.
  • De Botton, S., Sabri, S., Daugas, E., Zermati, Y., Guidotti, J.E., Hermine, O., Kroemer, G., Vainchenker, W. & Debili, N. (2002) Platelet formation is the consequence of caspase activation within megakaryocytes. Blood, 100, 13101317.
  • Fujisawa, K., Tani, P., O'Toole, T.E., Ginsberg, M.H. & McMillan, R. (1992) Different specificities of platelet-associated and plasma autoantibodies to platelet GPIIb-IIIa in patients with chronic immune thrombocytopenic purpura. Blood, 79, 14411446.
  • Gewirtz, A.M., Sacchetti, M.K., Bien, R. & Barry, W.E. (1986) Cell-mediated suppression of megakaryocytopoiesis in acquired amegakaryocytic thrombocytopenic purpura. Blood, 68, 619626.
  • Hedlund-Treutiger, I., Elinder, G., Wigzell, H., Grunewald, J. & Wahlstrom J. (2004) T cell receptor V gene usage by CD4+ and CD8+ peripheral blood T lymphocytes in immune thrombocytopenic purpura. Acta Paediatrica, 93, 633637.
  • Houwerzijl, E.J., Blom, N.R., Van Der Want, J.J., Esselink, M.T., Koornstra, J.J. & Smit, J.W. (2004) Ultrastructural study shows morphologic features of apoptosis and para-apoptosis in megakaryocytes from patients with idiopathic thrombocytopenic purpura. Blood, 103, 500506.
  • Houwerzijl, E.J., Blom, N.R., Van Der Want, J.J., Vellenga, E. & De Wolf, J.T. (2006) Megakaryocytic dysfunction in myelodysplastic syndromes and idiopathic thrombocytopenic purpura is in part due to different forms of cell death. Leukemia, 20, 19371942.
  • Isaka, Y., Kambayashi, J., Kimura, K., Matsumoto, M., Uehara, A., Hashikawa, K., Kamada, T., Imaizumi, M., Ashida, K. & Nakayama, H. (1990) Platelet production, clearance and distribution in patients with idiopathic thrombocytopenic purpura. Thrombosis Research, 60, 121131.
  • Kaluzhny, Y., Yu, G., Sun, S., Toselli, P.A., Nieswandt, B., Jackson, C.W. & Ravid, K. (2002) BclxL overexpression in megakaryocytes leads to impaired platelet fragmentation. Blood, 100, 16701678.
  • Kappers-Klunne, M.C., De Haan, M., Struijk, P.C. & Van Vliet, H.H. (2001) Serum thrombopoietin levels in relation to disease status in patients with immune thrombocytopenic purpura. British Journal of Haematology, 115, 10041006.
  • Kiefel, V., Santoso, S., Kaufmann, E. & Mueller, E.C. (1991) Autoantibodies against platelet glycoprotein GPIb/IX: a frequent finding in autoimmune thrombocytopenic purpura. British Journal of Haematology, 79, 256262.
  • Mattia, G., Vulcano, F., Milazzo, L., Barca, A., Macioce, G., Giampaolo, A. & Hassan, H.J. (2002) Different ploidy levels of megakaryocytes generated from peripheral or cord blood CD34+ cells are correlated with different levels of platelet release. Blood, 99, 888897.
  • McMillan, R. (2000) The pathogenesis of chronic immune (idiopathic) thrombocytopenic purpura. Seminars in Hematology, 37, 59.
  • McMillan, R., Wang, L., Tomer, A., Nichol, J. & Pistillo, J. (2004) Suppression of in vitro megakaryocyte production by antiplatelet autoantibodies from adult patients with chronic ITP. Blood, 103, 13641369.
  • Olsson, B., Andersson, P.O., Jernas, M., Jacobsson, S., Carlsson, B., Carlsson, L. & Wadenvik, H. (2003) T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura. Nature Medicine, 9, 11231124.
  • Olsson, B., Andersson, P.O., Jacobsson, S., Carlsson, L. & Wadenvik, H. (2005) Disturbed apoptosis of T-cells in patients with active idiopathic thrombocytopenic purura. Thrombosis and Haemostasis, 93, 139144.
  • Panitsas, F.P., Theodoropoulou, M., Kouraklis, A., Karakantza, M., Theodorou, G.L., Zoumbos, N.C., Maniatis, A. & Mouzaki, A. (2004) Adult chronic idiopathic thrombocytopenic purpura (ITP) is the manifestation of a type-1 polarized immune response. Blood, 103, 26452647.
  • Patel, S.R., Hartwig, J.H. & Italiano, J.E. (2005) The biogenesis of platelets from megakaryocyte proplatelets. The Journal of Clinical Investigation, 115, 33483354.
  • Porcelijn, L., Folman, C.C., Bossers, B., Huiskes, E., Overbeeke, M.A., V D Schoot, C.E., De Haas, M. & Von Dem Borne, A.E. (1998) The diagnostic value of thrombopoietin level measurements in thrombocytopenia. Thrombosis and Haemostasis, 79, 11011105.
  • Sanz, C., Benet, I., Richard, C., Badia, B., Andreu, E.J., Prosper, F. & Fernandez-Luna, J.L. (2001) Antiapoptotic protein Bcl-x(L) is up-regulated during megakaryocytic differentiation of CD34(+) progenitors but is absent from senescent megakaryocytes. Experimental Hematology, 29, 728735.
  • Sun, L., Hwang, W.Y. & Aw, S.E. (2006) Biological characteristics of megakaryocytes: specific lineage commitment and associated disorders. The International Journal of Biochemistry & Cell Biology, 38, 18211826.
  • Ware, R.E. & Howard, T.A. (1993) Phenotypic and clonal analysis of T lymphocytes in childhood immune thrombocytopenic purpura. Blood, 82, 21372142.
  • Yoshimura, C., Nomura, S., Nagahama, M., Ozaki, Y., Kagawa, H. & Fukuhara, S. (2000) Plasma-soluble Fas (APO-1, CD95) and soluble Fas ligand in immune thrombocytopenic purpura. European Journal of Haematology, 64, 219224.
  • Zhang, Y., Lorre, K., De Boer, M. & Ceuppens J.L. (1997) B7-blocking agents, alone or in combination with cyclosporin A, induce antigen-specific anergy of human memory T cells. Journal of Immunology, 158, 47344740.
  • Zhang, L., Zhao, H., Sun, A., Lu, S., Liu, B., Tang, F., Feng, Y., Zhao, L., Yang, R. & Han, Z.C. (2004) Early down-regulation of Bcl-xL expression during megakaryocytic differentiation of thrombopoietin-induced CD34+ bone marrow cells in essential thrombocythemia. Haematologica, 89, 11991206.
  • Zhang, F., Chu, X., Wang, L., Zhu, Y., Li, L., Ma, D., Peng, J. & Hou, M. (2006) Cell-mediated lysis of autologous platelets in chronic idiopathic thrombocytopenic purpura. European Journal of Haematology, 76, 427431.