These authors contributed equally to this work.
Gene expression profiling of CD34+ cells in patients with the 5q− syndrome
Article first published online: 3 OCT 2007
British Journal of Haematology
Volume 139, Issue 4, pages 578–589, November 2007
How to Cite
Boultwood, J., Pellagatti, A., Cattan, H., Lawrie, C. H., Giagounidis, A., Malcovati, L., Porta, M. G. D., Jädersten, M., Killick, S., Fidler, C., Cazzola, M., Hellström-Lindberg, E. and Wainscoat, J. S. (2007), Gene expression profiling of CD34+ cells in patients with the 5q− syndrome. British Journal of Haematology, 139: 578–589. doi: 10.1111/j.1365-2141.2007.06833.x
- Issue published online: 8 OCT 2007
- Article first published online: 3 OCT 2007
- Received 1 July 2007; accepted for publication 31 July 2007
Table SI. Patients’ clinical details.
Figure S1. Gene network for the significantly differentially expressed genes between 5q- syndrome and healthy controls. Genes in red are up-regulated in 5q- syndrome and genes in green are down-regulated in 5q- syndrome. Networks were generated in Ingenuity, specifying the fold change as the criterium of interest. The software produces a graph that identifies direct and indirect interactions between genes (the most highly connected network is shown).
Figure S2. Expression levels of the miR-143, miR-145 and miR-378 microRNA genes in patients with the 5q- syndrome, in patients with RA and a normal karyotype and in healthy controls.
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