• Chang, M., Nakagawa, P.A., Williams, S.A., Schwartz, M.R., Imfeld, K.L., Buzby, J.S. & Nugent, D.J. (2003) Immune thrombocytopenic purpura (ITP) plasma and purified ITP monoclonal autoantibodies inhibit megakaryocytopoiesis in vitro. Blood, 102, 887895.
  • Davis, J.C. Jr, Totoritis, M.C., Rosenberg, J., Sklenar, T.A. & Wofsy, D. (2001) Phase I clinical trial of a monoclonal antibody against CD40-ligand (IDEC-131) in patients with systemic lupus erythematosus. Journal of Rheumatology, 28, 95101.
  • Durie, F.H., Fava, R.A., Foy, T.M., Aruffo, A., Ledbetter, J.A. & Noelle, R.J. (1993) Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40. Science, 261, 13281330.
  • Im, S.H., Barchan, D., Maiti, P.K., Fuchs, S. & Souroujon, M.C. (2001) Blockade of CD40 ligand suppresses chronic experimental myasthenia gravis by down-regulation of Th1 differentiation and up-regulation of CTLA-4. Journal of Immunology, 166, 68936898.
  • Jiang, H. & Chess, L. (2004) An integrated view of suppressor T cell subsets in immunoregulation. Journal of Clinical Investigation, 114, 11981208.
  • Kalunian, K.C., Davis, J.C. Jr, Merrill, J.T., Totoritis, M.C. & Wofsy, D. (2002) Treatment of systemic lupus erythematosus by inhibition of T cell costimulation with anti-CD154: a randomized, double-blind, placebo-controlled trial. Arthritis and Rheumatism, 46, 32513258.
  • Karpatkin, S. (1997) Autoimmune (idiopathic) thrombocytopenic purpura. Lancet, 349, 15311536.
  • Kawai, T., Andrews, D., Colvin, R.B., Sachs, D.H. & Cosimi, A.B. (2000) Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. Nature Medicine, 6, 114.
  • Kuwana, M., Kawakami, Y. & Ikeda, Y. (2003) Suppression of autoreactive T-cell response to glycoprotein IIb/IIIa by blockade of CD40/CD154 interaction: implications for treatment of immune thrombocytopenic purpura. Blood, 101, 621623.
  • Kuwana, M., Nomura, S., Fujimura, K., Nagasawa, T., Muto, Y., Kurata, Y., Tanaka, S. & Ikeda, Y. (2004) Effect of a single injection of humanized anti-CD154 monoclonal antibody on the platelet-specific autoimmune response in patients with immune thrombocytopenic purpura. Blood, 103, 12291236.
  • Stasi, R., Del Poeta, G., Stipa, E., Evangelista, M.L., Trawinska, M.M., Cooper, N. & Amadori, S. (2007) Response to B-cell depleting therapy with rituximab reverts the abnormalities of T-cell subsets in patients with idiopathic thrombocytopenic purpura. Blood, 110, 29242930.
  • Xu, H., Tadaki, D.K., Elster, E.A., Burkly, L.C., Berning, J.D., Cruzata, F., Kampen, R.L., Montgomery, S.P., Patterson, N.B., Harlan, D.M. & Kirk, A.D. (2002) Humanized anti-CD154 antibody therapy for the treatment of allograft rejection in nonhuman primates. Transplantation, 74, 940943.