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Table SI. Mean transferrin saturation (%) ± SE by TMPRSS6 rs4820268 genotype, in six subgroups based on sex, menopause status and HFE C282Y homozygous or not.

Table SII. Mean serum iron (μmol/l) ± SE by TMPRSS6 rs4820268 genotype among six subgroups based on sex, menopause status and HFE C282Y homozygous or not.

Table SIII. Mean serum transferrin (g/l) ± SE by TF rs3811647 genotype among six subgroups based on sex, menopause status and HFE C282Y homozygous or not.

Table SIV. Mean serum transferrin (g/l) ± SE by TF rs1358024 genotype among six subgroups based on sex, menopause status and HFE C282Y homozygous or not.

Table SV. Mean serum ferritin in C282Y homozygotes by rs235756 BMP2 genotype from two studies: Milet et al. 2007 and this study. Milet gave a single result adjusted for age and sex, for comparison HealthIron results are shown adjusted only for age.

Appendix SI. List of SNPs genotyped in position order, updated to dbSNP version 129. The non-dbSNPs from NHLBI resequencing are shown as Gene position (see accession numbers in the methods) followed by UCSC May 06 coordinates.

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