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References

  • Alvarez-Hernández, X., Licéaga, J., McKay, I.C. & Brock, J.H. (1989) Induction of hypoferremia and modulation of macrophage iron metabolism by tumor necrosis factor. Laboratory Investigation, 61, 319322.
  • Auerbach, M. & Ballard, H. (2010) Clinical use of intravenous iron: administration, efficacy, and safety. Hematology. American Society of Hematology. Education Program, 2010, 338347.
  • Auerbach, M., Ballard, H., Trout, J.R., McIlwain, M., Ackerman, A., Bahrain, H., Balan, S., Barker, L. & Rana, J. (2004) Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: a multi-center, open-label, randomized trial. Journal of Clinical Oncology, 22, 13011307.
  • Bastit, L., Vandebroek, A., Altintas, S., Gaede, B., Pintér, T., Suto, T.S., Mossman, T.W., Smith, K.E. & Vansteenkiste, J.F. (2008) Randomized, multicenter, controlled trial comparing the efficacy and safety of darbepoetin alpha administered every 3 weeks with or without intravenous iron in patients with chemotherapy-induced anemia. Journal of Clinical Oncology, 26, 16111618.
  • Beaumont, C. & Canonne-Hergaux, F. (2005) Erythrophagocytose et recyclage du fer héminique dans les conditions normales et pathologiques; régulation par l’hepcidine. Transfusion Clinique et Biologique, 12, 123130.
  • Bergamaschi, G., Di Sabatino, A., Albertini, R., Ardizzone, S., Biancheri, P., Bonetti, E., Cassinotti, A., Cazzola, P., Markopoulos, K., Massari, A., Rosti, V., Porro, G.B. & Corazza, G.R. (2010) Prevalence and pathogenesis of anemia in inflammatory bowel disease. Influence of anti-tumor necrosis factor-alpha treatment. Haematologica, 95, 199205.
  • Brasse-Lagnel, C., Karim, Z., Letteron, P., Bekri, S., Bado, A. & Beaumont, C. (2011) Intestinal DMT1 cotransporter is downregulated by hepcidin via proteasome-internalization and degradation. Gastroenterology, 140, 12611271.
  • Brugnara, C., Laufer, M.R., Friedman, A.J., Bridges, K. & Platt, O. (1994) Reticulocyte haemoglobin content (CHr): early indicator of iron deficiency and response to therapy. Blood, 83, 31003101.
  • Burpee, T., Mitchell, P., Fishman, D., Islam, S., Nemeth, E., Westerman, M., Wessling-Resnick, M. & Grand, R.J. (2011) Intestinal ferroportin expression in pediatric Crohn’s disease. Inflammatory Bowel Diseases, 17, 524531.
  • Busbridge, M., Griffiths, C., Ashby, D., Gale, D., Jayantha, A., Sanwaiya, A. & Chapman, R.S. (2009) Development of a novel immunoassay for the iron regulatory peptide hepcidin. British Journal of Biomedical Science, 66, 150157.
  • Caro, J.J., Salas, M., Ward, A. & Goss, G. (2001) Anemia as an independent prognostic factor for survival in patients with cancer: a systemic, quantitative review. Cancer, 91, 22142221.
  • Cartwright, G.E. (1966) The anemia of chronic disorders. Seminars in Hematology, 3, 351375.
  • Cavill, I., Auerbach, M., Bailie, G.R., Barrett-Lee, P., Beguin, Y., Kaltwasser, P., Littlewood, T., Macdougall, I.C. & Wilson, K. (2006) Iron and the anaemia of chronic disease: a review and strategic recommendations. Current Medical Research and Opinion, 22, 731737.
  • Cazzola, M., Ponchio, L., de Benedetti, F., Ravelli, A., Rosti, V., Beguin, Y., Invernizzi, R., Barosi, G. & Martini, A. (1996) Defective iron supply for erythropoiesis and adequate endogenous erythropoietin production in the anemia associated with systemic-onset juvenile chronic arthritis. Blood, 87, 48244830.
  • Chasis, J.A. & Mohandas, N. (2008) Erythroblastic islands: niches for erythropoiesis. Blood, 112, 470478.
  • Cook, J.D., Skikne, B.S. & Baynes, R.D. (1993) Serum transferrin receptor. Annual Review of Medicine, 44, 6374.
  • Cooper, A., Mikhail, A., Lethbridge, M.W., Kemeny, D.M. & Macdougall, I.C. (2004) Pentoxifylline improves hemoglobin levels in patients with erythropoietin-resistant anemia in renal failure. Journal of the American Society of Nephrology, 15, 18771882.
  • Coyne, D.W., Kapoian, T., Suki, W., Singh, A.K., Moran, J.E., Dahl, N.V. & Rizkala, A.R.; DRIVE Study Group. (2007) Ferric gluconate is highly efficacious in anemic hemodialysis patients with high serum ferritin and low transferrin saturation: results of the Dialysis Patients’ Response to IV Iron with Elevated Ferritin (DRIVE) Study. Journal of the American Society of Nephrology, 18, 975984.
  • Dallalio, G., Law, E. & Means, Jr, R.T. (2006) Hepcidin inhibits in vitro erythroid colony formation at low erythropoietin concentrations. Blood, 107, 27022704.
  • Dallman, P.R., Yip, R. & Johnson, C. (1984) Prevalence and causes of anemia in the United States, 1976 to 1980. American Journal of Clinical Nutrition, 39, 437445.
  • Dangsuwan, P. & Manchana, T. (2010) Blood transfusion reduction with intravenous iron in gynecologic patients receiving chemotherapy. Gynecologic Oncology, 116, 522525.
  • Demirag, M.D., Haznedaroglu, S., Sancak, B., Konca, C., Gulbahar, O., Ozturk, M.A. & Goker, B. (2009) Circulating hepcidin in the crossroads of anemia and inflammation associated with rheumatoid arthritis. Internal Medicine, 48, 421426.
  • Doyle, M.K., Rahman, M.U., Han, C., Han, J., Giles, J., Bingham, C.O. & Bathon, J. (2009) Treatment with infliximab plus methotrexate improves anemia in patients with rheumatoid arthritis independent of improvement in other clinical outcome measures-a pooled analysis from three large, multicenter, double-blind, randomized clinical trials. Seminars in Arthritis and Rheumatism, 39, 123131.
  • Faquin, W.C., Schneider, T.J. & Goldberg, M.A. (1992) Effect of inflammatory cytokines on hypoxia-induced erythropoietin production. Blood, 79, 19871994.
  • Ferrari, P., Mallon, D., Trinder, D. & Olynyk, J.K. (2010) Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease. Nephrology (Carlton), 15, 344349.
  • Ferrucci, L. & Balducci, L. (2008) Anemia of aging: the role of chronic inflammation and cancer. Seminars in Hematology, 2008, 242249.
  • Ferrucci, L., Semba, R.D., Guralnik, J.M., Ershler, W.B., Bandinelli, S., Patel, K.V., Sun, K., Woodman, R.C., Andrews, N.C., Cotter, R.J., Ganz, T., Nemeth, E. & Longo, D.L. (2010) Proinflammatory state, hepcidin, and anemia in older persons. Blood, 115, 38103816.
  • Fitzsimons, E.J., Houston, T., Munro, R., Sturrock, R.D., Speekenbrink, A.B. & Brock, J.H. (2002) Erythroblast iron metabolism and serum soluble transferrin receptor values in the anemia of rheumatoid arthritis. Arthritis and Rheumatism, 47, 166171.
  • Ganz, T., Olbina, G., Girelli, D., Nemeth, E. & Westerman, M. (2008) Immunoassay for human hepcidin. Blood, 112, 42924297.
  • Gasche, C., Lomer, M.C., Cavill, I. & Weiss, G. (2004) Iron, anaemia and inflammatory bowel diseases. Gut, 53, 11901197.
  • Glaspy, J., Crawford, J., Vansteenkiste, J., Henry, D., Rao, S., Bowers, P., Berlin, J.A., Tomita, D., Bridges, K. & Ludwig, H. (2010) Erythropoiesis-stimulating agents in oncology: a study-level meta-analysis of survival and other safety outcomes. British Journal of Cancer, 102, 301315.
  • Goodnough, L.T., Nemeth, E. & Ganz, T. (2010) Detection, evaluation and management of iron-restricted erythropoiesis. Blood, 116, 47544761.
  • Hedenus, M., Birgegård, G., Näsman, P., Ahlberg, L., Karlsson, T., Lauri, B., Lundin, J., Lärfars, G. & Osterborg, A. (2007) Addition of intravenous iron to epoetin beta increases hemoglobin response and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: a randomized multicenter study. Leukemia, 21, 627632.
  • Henke, M., Laszig, R., Rübe, C., Schäfer, U., Haase, K.D., Schilcher, B., Mose, S., Beer, K., Burger, U., Dougherty, C. & Frommhold, F. (2003) Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet, 362, 12551260.
  • Henry, D.H., Beall, G.N., Benson, C.A., Carey, J., Cone, L.A., Eron, L.J., Fiala, M., Fischl, M.A., Gabin, S.J., Gottlieb, M.S., Galpin, J.E., Groopman, J.E., Hooton, T.M., Jemsek, J.G., Levine, R.L., Miles, S.A., Rinehart, J.J., Rios, A., Robbins, W.J., Ruckdeschel, J.C., Smith, J.A., Spotswood, L.S., Starrett, B., Toney, J., Zalusky, R., Abels, R.I., Bryant, E.C., Larholt, K.M., Sampson, A.R. & Rudnick, S.A. (1992) Recombinant human erythropoietin in the treatment of anemia associated with human immunodeficiency virus (HIV) infection and zidovudine therapy. Overview of four clinical trials. Annals of Internal Medicine, 117, 739748.
  • Henry, D.H., Dahl, N.V., Auerbach, M., Tchekmedyian, S. & Laufman, L.R. (2007) Intravenous ferric gluconate significantly improves response to epoetin alfa versus oral iron or no iron in anemic patients with cancer receiving chemotherapy. The Oncologist, 12, 231242.
  • Hohaus, S., Massini, G., Giachelia, M., Vannata, B., Bozzoli, V., Cuccaro, A., D’Alo, F., Larocca, L.M., Raymakers, R.A., Swinkels, D.W., Voso, M.T. & Leone, G. (2010) Anemia in Hodgkin’s lymphoma: the role of interleukin-6 and hepcidin. Journal of Clinical Oncology, 28, 25382543.
  • Jenkins, J.K. (2007) Erythropoiesis-stimulating agents (ESA). Available at: http://www.fda.gov/NewsEvents/Testimony/ucm110908.htm.
  • Johnson, C.S., Keckler, D.J., Topper, M.I., Braunschweiger, P.G. & Furmanski, P. (1989) In vivo hematopoietic effects of recombinant interleukin-1 alpha in mice: stimulation of granulocytic, monocytic, megakaryocytic, and early erythroid progenitors, suppression of late-stage erythropoiesis, and reversal of erythroid suppression with erythropoietin. Blood, 73, 678683.
  • Kaltwasser, J.P., Kessler, U., Gottschalk, R., Stucki, G. & Möller, B. (2001) Effect of recombinant human erythropoietin and intravenous iron on anemia and disease activity in rheumatoid arthritis. Journal of Rheumatology, 28, 24302436.
  • Kemna, E.H., Tjalsma, H., Podust, V.N. & Swinkels, D.M. (2007) Mass spectrometry-based hepcidin measurements in serum and urine: analytical aspects and clinical implications. Clinical Chemistry, 53, 620628.
  • Kim, Y.T., Kim, S.W., Yoon, B.S., Cho, H.J., Nahm, E.J., Kim, S.H., Kim, J.H. & Kim, J.W. (2007) Effect of intravenously administered iron sucrose on the prevention of anemia in the cervical cancer patients treated with concurrent chemoradiotherapy. Gynecologic Oncology, 105, 199204.
  • Kroot, J.J., Kemna, E.H., Bansal, S.S., Busbridge, M., Campostrini, N., Girelli, D., Hider, R.C., Koliaraki, V., Mamalaki, A., Olbina, G., Tomosugi, N., Tselepis, C., Ward, D.G., Ganz, T., Hendriks, J.C. & Swinkels, D.W. (2009) Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization. Haematologica, 2009, 17481752.
  • Lee, P., Peng, H., Gelbart, T., Wang, L. & Beutler, E. (2005) Regulation of hepcidin transcription by interleukin-1 and interleukin-6. Proceedings of the National Academy of Science of the United States of America, 102, 19061910.
  • Littlewood, T.J. & Alikhan, R. (2008) The use of intravenous iron in patients with cancer-related anaemia. British Journal of Haematology, 141, 751756.
  • Littlewood, T.J., Bajetta, E., Nortier, J.W., Vercammen, E. & Rapoport, B. (2001) Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: results of a randomized, double-blind, placebo-controlled trial. Journal of Clinical Oncology, 19, 28652874.
  • Littlewood, T.J., Zagari, M., Pallister, C. & Perkins, A. (2003) Baseline and early treatment factors are not clinically useful for predicting individual response to erythropoietin in anemic cancer patients. The Oncologist, 8, 99107.
  • Locatelli, F., Covic, A., Eckardt, K.U., Wiecek, A. & Vanholder, R. (2009) Anaemia management in patients with chronic kidney disease: a position statement by the Anaemia Working Group of European Renal Best Practice (ERBP). Nephrology Dialysis Transplantation, 24, 348354.
  • Ludwig, H., Sundal, E., Pecherstorfer, M., Leitgeb, C., Bauernhofer, T., Beihauer, A., Samonigg, H., Kappeler, A.W. & Fritz, E. (1995) Recombinant human erythropoietin for the correction of cancer associated anemia with and without concomitant cytotoxic chemotherapy. Cancer, 76, 23192329.
  • Maes, K., Nemeth, E., Roodman, G.D., Huston, A., Esteve, F., Freytes, C., Callander, N., Katodritou, E., Tussing-Humphreys, L., Rivera, S., Vanderkerken, K., Lichtenstein, A. & Ganz, T. (2010) In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2. Blood, 116, 36353644.
  • Malope, B.I., MacPhail, A.P., Alberts, M. & Hiss, D.C. (2001) The ratio of serum transferrin receptor and serum ferritin in the diagnosis of iron status. British Journal of Haematology, 115, 8489.
  • Mast, A.E., Blinder, M.A., Gronowski, A.M., Chumley, C. & Scott, M.G. (1998) Clinical utility of the soluble transferrin receptor and comparison with serum ferritin in several populations. Clinical Chemistry, 44, 4551.
  • de Mast, Q., van Dongen-Lases, E.C., Swinkels, D.W., Nieman, A.E., Roestenberg, M., Druilhe, P., Arens, T.A., Luty, A.J., Hermsen, C.C., Sauerwein, R.W. & van der Ven, A.J. (2009) Mild increases in serum hepcidin and interleukin-6 concentrations impair iron incorporation in haemoglobin during an experimental human malaria infection. British Journal of Haematology, 145, 657664.
  • Means, Jr, R.T. (1995) Pathogenesis of the anemia of chronic disease: a cytokine-mediated anemia. Stem Cells (Dayton, Ohio), 13, 3237.
  • Means, Jr, R.T. & Krantz, S.B. (1991) Inhibition of human erythroid-colony forming units by gamma interferon can be corrected by recombinant human erythropoietin. Blood, 78, 25642567.
  • Miller, C.B., Jones, R.J., Piantadosi, S., Abeloff, M.D. & Spivak, J.L. (1990) Decreased erythropoietin response in patients with the anemia of cancer. New England Journal of Medicine, 322, 16891692.
  • Mitlyng, B.L., Singh, J.A., Furne, J.K., Ruddy, J. & Levitt, M.D. (2006) Use of breath carbon monoxide measurements to assess erythrocyte survival in subjects with chronic diseases. American Journal of Hematology, 81, 432438.
  • Moreland, L.W., Baumgartner, S.W., Schiff, M.H., Tindall, E.A., Fleischmann, R.M., Weaver, A.L., Ettlinger, R.E., Cohen, S., Koopman, W.J., Mohler, K., Widmer, M.B. & Blosch, C.M. (1997) Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. New England Journal of Medicine, 337, 141147.
  • Moreno, F., Sanz-Guajardo, D., López-Gómez, J.M., Jofre, R. & Valderrábano, F. (2000) Increasing the hematocrit has a beneficial effect on quality of life and is safe in selected hemodialysis patients. Spanish Cooperative Renal Patients Quality of Life Study Group of the Spanish Society of Nephrology. Journal of the American Society of Nephrology, 11, 335342.
  • Murphy, A.T., Witcher, D.R., Luan, P. & Wroblewski, V.J. (2007) Quantitation of hepcidin from human and mouse serum using liquid chromatography tandem mass spectrometry. Blood, 110, 10481054.
  • Nemeth, E. & Ganz, T. (2009) The role of hepcidin in iron metabolism. Acta Haematologica, 122, 7886.
  • Nemeth, E., Rivera, S., Gabayan, V., Keller, C., Taudorf, S., Pedersen, B.K. & Ganz, T. (2004a) IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. Journal of Clinical Investigation, 113, 12711276.
  • Nemeth, E., Tuttle, M.S., Powelson, J., Vaughn, M.B., Donovan, A., Ward, D.M., Ganz, T. & Kaplan, J. (2004b) Hepcidin regulates iron efflux by binding to ferroportin and inducing its internalization. Science, 306, 20902093.
  • Nissenson, A.R., Goodnough, L.T. & Dubois, R.W. (2003) Anemia: not just an innocent bystander. Archives of Internal Medicine, 163, 14001404.
  • Nordström, D., Lindroth, Y., Marsal, L., Hafström, I., Henrich, C., Rantapää-Dahlqvist, S., Engström-Laurent, A., Fyhrquist, F. & Friman, C. (1997) Availability of iron and degree of inflammation modifies the response to recombinant human erythropoietin when treating anemia of chronic disease in patients with rheumatoid arthritis. Rheumatology International, 17, 6773.
  • Opasich, C., Cazzola, M., Scelsi, L., de Feo, S., Bosimini, E., Lagioia, R., Febo, O., Ferrari, R., Fucili, A., Moratti, R., Tramarin, R. & Tavazzi, L. (2005) Blunted erythropoietin production and defective iron supply for erythropoiesis as major causes of anaemia in patients with chronic heart failure. European Heart Journal, 26, 22322237.
  • Papadaki, H.A., Kritikos, H.D., Valatas, V., Boumpas, D.T. & Eliopoulos, G.D. (2002) Anemia of chronic disease in rheumatoid arthritis is associated with increased apoptosis of bone marrow erythroid cells: improvement following anti-tumor necrosis factor-alpha antibody therapy. Blood, 100, 474482.
  • Park, C.H., Valore, E.V., Waring, A.J. & Ganz, T. (2001) Hepcidin, a urinary antimicrobial peptide synthesized in the liver. The Journal of Biological Chemistry, 276, 78067810.
  • Pedrazzoli, P., Farris, A., Del Prete, S., Del Gaizo, F., Ferrari, D., Bianchessi, C., Colucci, G., Desogus, A., Gamucci, T., Pappalardo, A., Fornarini, G., Pozzi, P., Fabi, A., Labianca, R., Di Costanzo, F., Secondino, S., Crucitta, E., Apolloni, F., Del Santo, A. & Siena, S. (2008) Randomized trial of intravenous iron supplementation in patients with chemotherapy-related anemia without iron deficiency treated with darbepoetin alpha. Journal of Clinical Oncology, 26, 16191625.
  • Peeters, H.R., Jongen-Lavrencic, M., Vreugdenhil, G. & Swaak, A.J. (1996) Effect of recombinant human erythropoietin on anaemia and disease activity in patients with rheumatoid arthritis and anaemia of chronic disease: a randomised placebo controlled double blind 52 weeks clinical trial. Annals of the Rheumatic Diseases, 55, 739744.
  • Perlstein, T.S., Pande, R., Berliner, R. & Vanasse, G.J. (2011) Prevalence of 25-hydroxyvitamin D deficiency in subgroups of elderly persons with anemia: association with anemia of inflammation. Blood, 117, 28002806.
  • Pfeffer, M.A., Burdmann, E.A., Chen, C.Y., Cooper, M.E., de Zeeuw, D., Eckardt, K.U., Feyzi, J.M., Ivanovich, P., Kewalramani, R., Levey, A.S., Lewis, E.F., McGill, J.B., McMurray, J.J., Parfrey, P., Parving, H.H., Remuzzi, G., Singh, A.K., Solomon, S.D. & Toto, R.; TREAT Investigators. (2009) A trial of darbepoietin alfa in type 2 diabetes and chronic kidney disease. New England Journal of Medicine, 361, 20192032.
  • Pincus, T., Olsen, N.J., Russell, I.J., Wolfe, F., Harris, E.R., Schnitzer, T.J., Boccagno, J.A. & Krantz, S.B. (1990) Multicenter study of recombinant human erythropoietin in correction of anemia in rheumatoid arthritis. American Journal of Medicine, 89, 161168.
  • Poli, M., Girelli, D., Campostrini, N., Maccarinelli, F., Finazzi, D., Luscieti, S., Nai, A. & Arosio, P. (2011) Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo. Blood, 117, 9971004.
  • Punnonen, K., Irjala, K. & Rajamäki, A. (1997) Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood, 89, 10521057.
  • Rivera, S., Nemeth, E., Gabayan, V., Lopez, M.A., Farshidi, D. & Ganz, T. (2005) Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs. Blood, 106, 21962199.
  • Rizzo, J.D., Brouwers, M., Hurley, P., Seidenfeld, J., Arcasoy, M.O., Spivak, J.L., Bennett, C.L., Bohlius, J., Evanchuk, D., Goode, M.J., Jakubowski, A.A., Regan, D.H. & Somerfield, M.R.; American Society of Clinical Oncology; American Society of Hematology. (2010) American Society of Clinical Oncology/American Society of Hematology clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer. Blood, 116, 40454059.
  • Roy, C.N., Mak, H.H., Akpan, I., Losyev, G., Zurakowski, D. & Andrews, N.C. (2007) Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation. Blood, 109, 40384044.
  • Sasu, B.J., Cooke, K.S., Arvedson, T.L., Plewa, C., Ellison, A.R., Sheng, J., Winters, A., Juan, T., Li, H., Begley, C.G. & Molineux, C. (2010) Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia. Blood, 115, 36163624.
  • Schreiber, S., Howaldt, S., Schnoor, M., Nikolaus, S., Bauditz, J., Gasché, C., Lochs, H. & Raedler, A. (1996) Recombinant erythropoietin for the treatment of anemia in inflammatory bowel disease. New England Journal of Medicine, 334, 619623.
  • Semba, R.D., Shah, N. & Vlahov, D. (2001) Improvement of anemia among HIV-infected injection drug users receiving highly active antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes, 26, 315319.
  • Sharma, S., Nemeth, E., Chen, Y.H., Goodnough, J., Huston, A., Roodman, G.D., Ganz, T. & Lichtenstein, A. (2008) Involvement of hepcidin in the anemia of multiple myeloma. Clinical Cancer Research, 14, 32623267.
  • Sinclair, A.M., Coxon, A., McCaffery, I., Kaufman, S., Paweletz, K., Liu, L., Busse, L., Swift, S., Elliott, S. & Begley, C.G. (2010) Functional erythropoietin receptor is undetectable in endothelial, cardiac, neuronal, and renal cells. Blood, 115, 42644272.
  • Singh, A.K., Szczech, L., Tang, K.L., Barnhart, H., Sapp, S., Wolfson, M. & Reddan, D.; CHOIR Investigators. (2006) Correction of anemia with epoetin alfa in chronic kidney disease. New England Journal of Medicine, 355, 20852098.
  • Skikne, B.S. (2008) Serum transferrin receptor. American Journal of Hematology, 83, 872875.
  • Smith, Jr, R.E., Tchekmedyian, N.S., Chan, D., Meza, L.A., Northfelt, D.W., Patel, R., Austin, M., Colowick, A.B., Rossi, G. & Glaspy, J. (2003) A dose- and schedule-finding study of darbepoetin alpha for the treatment of chronic anaemia of cancer. British Journal of Cancer, 88, 18511858.
  • Song, S.N., Tomosugi, N., Kawabata, H., Ishikawa, T., Nishikawa, T. & Yoshizaki, K. (2010) Down-regulation of hepcidin resulting from long-term treatment with an anti-IL-6 receptor antibody (tocilizumab) improves anemia of inflammation in multicentric Castleman disease. Blood, 116, 36273634.
  • Steensma, D.P., Sloan, J.A., Dakhil, S.R., Dalton, R., Kahanic, S.P., Prager, D.J., Stella, P.J., Rowland, Jr, K.M., Novotny, P.J. & Loprinzi, C.L. (2011) Phase III, randomized study of the effects or parenteral iron, oral iron, or no iron supplementation on the erythropoietic response to darbepoetin alfa for patients with chemotherapy-associated anemia. Journal of Clinical Oncology, 29, 97105.
  • Suominen, P., Möttönen, T., Rajamäki, A. & Irjala, K. (2000) Single values of serum transferrin receptor and transferrin receptor index can be used to detect true and functional iron deficiency in rheumatoid arthritis patients with anemia. Arthritis and Rheumatism, 43, 10161020.
  • Swift, S., Ellison, A.R., Kassner, P., McCaffery, I., Rossi, J., Sinclair, A.M., Begley, C.G. & Elliott, S. (2010) Absence of functional EpoR expression in human tumor cell lines. Blood, 115, 42544263.
  • Theurl, I., Aigner, E., Theurl, M., Nairz, M., Seifert, M., Schroll, A., Sonnweber, T., Eberwein, L., Witcher, D.R., Murphy, A.T., Wroblewski, V.J., Wurz, E., Datz, C. & Weiss, G. (2009) Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications. Blood, 113, 52775286.
  • Theurl, I., Finkenstedt, A., Schroll, A., Nairz, M., Sonnweber, T., Bellmann-Weiler, R., Theurl, M., Seifert, M., Wroblewski, V.J., Murphy, A.T., Witcher, D., Zoller, H. & Weiss, G. (2010) Growth differentiation factor 15 in anaemia of chronic disease, iron deficiency anaemia and mixed type anaemia. British Journal of Haematology, 148, 449455.
  • Thomas, C. & Thomas, L. (2002) Biochemical markers and hematologic indices in the diagnosis of functional iron deficiency. Clinical Chemistry, 48, 10661076.
  • Truksa, J., Peng, H., Lee, P. & Beutler, E. (2006) Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6. Proceedings of the National Academy of Science of the United States of America, 103, 1028910293.
  • Vreugdenhil, G., Wognum, A.W., van Eijk, H.G. & Swaak, A.J. (1990a) Anaemia in rheumatoid arthritis: the role of iron, vitamin B12, and folic acid deficiency, and erythropoietin responsiveness. Annals of the Rheumatic Diseases, 49, 9398.
  • Vreugdenhil, G., Löwenberg, B., van Eijk, H.G. & Swaak, A.J. (1990b) Anaemia of chronic disease in rheumatoid arthritis. Raised serum interleukin-6 (IL-6) levels and effects of IL-6 and anti-IL-6 on in vitro erythropoiesis. Rheumatology International, 10, 127130.
  • Wang, L., Trebicka, E., Fu, Y., Elllenbogen, S., Hong, C.C., Babitt, J.L., Lin, H.Y. & Cherayil, B.J. (2011) The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease. Inflammatory Bowel Diseases, doi: 10.1002/ibd.21675. e-pub ahead of print.
  • Weiss, G. & Goodnough, L.T. (2005) Anemia of chronic disease. New England Journal of Medicine, 352, 10111023.
  • Wilson, J., Yao, G.L., Raftery, J., Bohlius, J., Brunskill, S., Sandercock, J., Bayliss, S., Moss, P., Stanworth, S. & Hyde, C. (2007) A systematic review and economic evaluation of epoetin alfa, epoetin beta and darbepoetin alpha in anaemia associated with cancer, especially that attributable to cancer treatment. Health Technology Assessment, 11, 1202.
  • Witzig, T.E., Silberstein, P.T., Loprinzi, C.L., Sloan, J.A., Novotny, P.J., Mailliard, J.A., Rowland, K.M., Alberts, S.R., Krook, J.E., Levitt, R. & Morton, R.F. (2005) Phase III, randomized, double-blind study of epoetin alfa compared with placebo in anemic patients receiving chemotherapy. Journal of Clinical Oncology, 23, 26062617.
  • Wright, J.R., Ung, Y.C., Julian, J.A., Pritchard, K.I., Whelan, T.J., Smith, C., Szechtman, B., Roa, W., Mulroy, L., Rudinskas, L., Gagnon, B., Okawara, G.S. & Levine, M.N. (2007) Randomized, double-blind, placebo-controlled trial of erythropoietin in non-small-cell lung cancer with disease-related anemia. Journal of Clinical Oncology, 25, 10271032.
  • Wrighting, D.M. & Andrews, N.C. (2006) Interleukin-6 induces hepcidin expression through STAT-3. Blood, 108, 32043209.
  • Yu, P.B., Hong, C.C., Sachidanandan, C., Babitt, J.L., Deng, D.Y., Hoyng, S.A., Lin, H.Y., Bloch, K.D. & Peterson, R.T. (2008) Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nature Chemical Biology, 4, 3341.
  • Zanjani, E.D., McGlave, P.B., Davies, S.F., Banisadre, M., Kaplan, M.E. & Sarosi, G.A. (1982) In vitro suppression of erythropoiesis by bone marrow adherent cells from some patients with fungal infection. British Journal of Haematology, 50, 479490.