Platinum sensitivity: treatment by specific hyposensitization


Dr G. M. Levene, The Institute of Dermatology, Homerton Grove, London E9 6BX.


An analytical chemist developed respiratory tract and cutaneous allergy to complex salts of platinum in the course of his work.

Specific hyposensitization was achieved by means of intradermal injections of allergen given in increasing doses. During the course of injections he developed symptoms and signs suggestive of a serum-sickness reaction.

The immunological significance of these phenomena was investigated.