Inhibition of reagin-mediated PCA reactions in baboons by the human IgG4 sub-class


Dr D. R. Stanworth, Department of Experimental Pathology, University of Birmingham, Medical School, Birmingham 15.


It has been shown that a human myeloma protein of the IgG4 sub-class, in contrast to myeloma proteins representative of the other three human IgG sub-classes, is capable of blocking PCA reactions in baboons mediated by human reaginic antibodies of the IgE class.