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Summary

The radioallergosorbent test (RAST) was performed with a purified allergen (DS 22) from cod, coupled to CNBr-activated cellulose discs. A 100% correlation was found between a positive RAST and the presence of clinical allergy to cod in fifty-six children as compared to a negative RAST in all sera from fifty-six allergic children tolerating fish. Positive results were obtained with discs treated with DS 22 in a concentration as low as 0.4 ng/ml.