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Summary

(1) Elevated IgE antibody to A.fumigatus is present in most patients with allergic bronchopulmonary aspergillosis, but not in the sera of patients with a variety of pulmonary conditions that contain A. fumigatus precipitins.

(2) The RAST assays for measuring IgE antibodies to this antigen are relatively simple to perform and have a practical clinical value.

(3) The exact pathophysiologic role of these IgE antibodies is not yet denned, and several hypotheses are proposed.