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Summary

Immediate asthmatic and urticarial reactions were provoked in an affected subject by ingestion of a commercial combination of three tetracylines. No reactions were elicited by the tetracyclines given separately or prepared together as a powder; this was perhaps due to tachyphylaxis, since a test with the commercial preparation 2 months later elicited the reactions again. No reactions were elicited by the blue coating of the commercial preparation or by tartrazine.