Phthalic anhydride asthma

Authors

  • EDWARD H. CHESTER,

    1. Department of Medicine, Case Western Reserve University, the Cleveland Veterans Administration Hospital and University Hospitals, Cleveland, Ohio 44106
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  • HOWARD J. SCHWARTZ,

    Corresponding author
    1. Department of Medicine, Case Western Reserve University, the Cleveland Veterans Administration Hospital and University Hospitals, Cleveland, Ohio 44106
      Dr Howard J. Schwartz, 111 J 1(W) Pulmonary Section A, Veterans Administration Hospital, 10701 East Boulevard, Cleveland, Ohio 44106, U.S.A.
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  • CHARLES B. PAYNE JR,

    1. Department of Medicine, Case Western Reserve University, the Cleveland Veterans Administration Hospital and University Hospitals, Cleveland, Ohio 44106
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  • STEPHEN GREENSTEIN

    1. Department of Medicine, Case Western Reserve University, the Cleveland Veterans Administration Hospital and University Hospitals, Cleveland, Ohio 44106
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Dr Howard J. Schwartz, 111 J 1(W) Pulmonary Section A, Veterans Administration Hospital, 10701 East Boulevard, Cleveland, Ohio 44106, U.S.A.

Summary

A patient with occupational asthma caused by phthalic anhydride is described. Inhalation challenges under laboratory control produced immediate and delayed asthmatic responses. Repeat exposure to phthalic anhydride after treatment with cromolyn sodium showed inhibition of the late but not the early bronchoconstrictive, asthmatic response.

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