Appraisal of skin tests with food extracts for diagnosis of food hypersensitivity

Authors

  • S. A. BOCK,

    Corresponding author
    1. Department of Pediatrics, National Jewish Hospital and Research Center, and the University of Colorado Medical Center, Denver, Colorado, U.S.A.
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  • W.-Y. LEE,

    1. Department of Pediatrics, National Jewish Hospital and Research Center, and the University of Colorado Medical Center, Denver, Colorado, U.S.A.
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  • L. REMIGIO,

    1. Department of Pediatrics, National Jewish Hospital and Research Center, and the University of Colorado Medical Center, Denver, Colorado, U.S.A.
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  • A. HOLST,

    1. Department of Pediatrics, National Jewish Hospital and Research Center, and the University of Colorado Medical Center, Denver, Colorado, U.S.A.
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  • C. D. MAY

    1. Department of Pediatrics, National Jewish Hospital and Research Center, and the University of Colorado Medical Center, Denver, Colorado, U.S.A.
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Dr S. A. Bock, Department of Pediatrics, National Jewish Hospital and Research Center, 3800 East Colfax Avenue, Denver, Colorado 80206, U.S.A.

Summary

Seventy-six children aged 5 months to 15 years who exhibited a net weal of 3.0 mm or greater to a puncture skin test with one or more of fourteen foods were subjected to double-blind food challenge. Confirmed reactions to double-blind food challenge were found to occur only with peanut, milk, egg and soybean. Puncture skin tests with 1:20 w/v concentration of food extracts identified all subjects who exhibited an adverse reaction during the double-blind food challenge. Performance of intradermal skin tests did not identify any additional subjects who reacted clinically to double-blind food challenge.

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