Clinical & Experimental Allergy

Comparison between ketotifen and DSCG in bronchial challenge


Dr R. Pauwels, Academic Hospital, Department of Chest Diseases, State University, Ghent, Belgium.


A double-blind cross-over study showed that orally taken ketotifen and inhaled DSCG have a comparable protective effect on allergen-induced bronchoconstriction. Both drugs significantly inhibit the immediate bronchial reaction after a 3 day treatment with either 1 mg ketotifen or 20 mg DSCG four times daily. Late reactions, which occurred in three out of the ten patients, were inhibited in two of the three patients by ketotifen as by DSCG.