Blood histamine levels after exercise testing


Dr M. G. Harries, Department of Clinical Immunology, Cardiothoracic Institute, Brompton Hospital, Fulham Road, London SW3 6HP.


Histamine has been measured in whole blood and in the plasma of twenty-three subjects following exercise testing of seventeen asthmatics and six normal controls. Whole blood histamine rose in both asthmatics and controls and was associated with a concomitant rise in the basophil count. Plasma histamine in the peripheral venous blood only rose in one patient who developed urticaria after exercise.