Potentiation by polymyxin B of the bronchoconstriction following allergen inhalation in patients with atopic asthma


Dr J. Rosniecki, Pneumonological Clinic of the Medical Academy, 90–153 Lodz, ul Kopcinskiego 22, Poland.


The effect of a single inhalation of allergen on bronchial reactivity to polymyxin B was studied in eight patients with hay fever. In winter the reaction to polymyxin B before and after inhalation of pollen allergen is measured by the FEV. In all patients bronchial reactivity to polymyxin B increased under the influence of allergen.