A double-blind trial comparing disodium cromoglycate (DSCG), and ketotifen in extrinsic asthmatic children

Authors

  • J. F. SCHUHL,

    Corresponding author
    1. Allergy and Clinical Immunology Unit, Dermatological Clinic, Clinical's Hospital-Faculty of Medicine, Montevideo, Uruguay
    Search for more papers by this author
  • D. HOLGADO DE CUESTA

    1. Allergy and Clinical Immunology Unit, Dermatological Clinic, Clinical's Hospital-Faculty of Medicine, Montevideo, Uruguay
    Search for more papers by this author

Prof. Adj. Dr J. F. Schuhl, Echevarriarza 3398 (Pocitos), Montevideo, Uruguay.

Summary

A double-blind non crossover trial comparing disodium cromoglycate (DSCG), with ketotifen, was carried out in twenty-seven extrinsic asthmatic children over 12 weeks. Assessment was made using symptom score and drug score charts. Both drugs showed a similar protective effect in the group studied. None of the subjects had to withdraw from the trial and no side-effects were noted in weight-curve, arterial pressure and pulse rate. PEFR values remained unchanged for both drugs throughout the trial. A non-significant tendency for additional corticosteroid support in the Ketotifen group was noted.

Ancillary