Serum and salivary immunoglobulin A and free secretory component in ulcerative colitis

Authors

  • T. J. MORRIS,

    1. Departments of Gastroenterology and Medical Microbiology, University Hospital of Wales, and Welsh National School of Medicine, Cardiff
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  • N. MATTHEWS,

    1. Departments of Gastroenterology and Medical Microbiology, University Hospital of Wales, and Welsh National School of Medicine, Cardiff
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  • J. RHODES

    Corresponding author
    1. Departments of Gastroenterology and Medical Microbiology, University Hospital of Wales, and Welsh National School of Medicine, Cardiff
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Dr John Rhodes, Consultant Gastroenterologist, Department of Gastroenterology, University Hospital of Wales, Cardiff.

Summary

Patients with ulcerative colitis have been investigated for evidence of defects in secretory immunity. Total serum IgA concentration, serum IgA antibody titres to Candida albicans, salivary IgA and free secretory component concentrations have been measured in thirty-six patients with ulcerative colitis and thirty-six normal controls. None of the parameters was significantly different between patients with proctitis and patients with extensive colitis or between the colitis patients and normal controls.

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