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An immunofluorescent study of the ampicillin rash
Article first published online: 27 APR 2006
DOI: 10.1111/j.1365-2222.1982.tb02528.x
1365-2222/asset/cover.gif?v=1&s=363d6ac7042b7535760df61b7393fd8e0a08e85f "Clinical & Experimental Allergy")
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How to Cite
GATTER, K. C. and BELL, J. I. (1982), An immunofluorescent study of the ampicillin rash. Clinical & Experimental Allergy, 12: 279–280. doi: 10.1111/j.1365-2222.1982.tb02528.x
Publication History
- Issue published online: 27 APR 2006
- Article first published online: 27 APR 2006
- (Received 1 September 1981; accepted for publication 16 November 1981)
- Abstract
- References
- Cited By
Summary
The aetiology of the ampicillin rash is uncertain although numerous theories have been proposed–mainly immunological. One such concerns the presence of anti-epithelial antibodies which have received conflicting reports in the literature. In this study, skin biopsies from three patients with a maculopapular ampicillin-rash were studied by immunofluorescence to investigate the presence of anti-epithelial antibodies. However immunofluorescence for IgG, IgM, IgA and C3 was completely negative so that we were unable to provide any support for this particular hypothesis.