Radioallergosorbent testing with p-tolyl monoisocyanate in toluene diisocyanate workers

Authors

  • B. T. BUTCHER,

    Corresponding author
    1. Clinical Immunology Section, Department of Medicine, Tulane Medical Center, New Orleans, Louisiana, U.S.A.
      Dr Brian T. Butcher, Clinical Immunology, Tulane Medical Center, 1700 Perdido Street, New Orleans, La 70112, U.S.A.
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  • C. E. O'NEIL,

    1. Clinical Immunology Section, Department of Medicine, Tulane Medical Center, New Orleans, Louisiana, U.S.A.
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  • M. A. REED,

    1. Clinical Immunology Section, Department of Medicine, Tulane Medical Center, New Orleans, Louisiana, U.S.A.
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  • E. SALVAGGIO

    1. Clinical Immunology Section, Department of Medicine, Tulane Medical Center, New Orleans, Louisiana, U.S.A.
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Dr Brian T. Butcher, Clinical Immunology, Tulane Medical Center, 1700 Perdido Street, New Orleans, La 70112, U.S.A.

Summary

Sera from 149 occupationally exposed toluene diisocyanate (TDI) workers were tested by RAST with p-tolyl monoisocyanate human serum albumin (TMI-HSA). Of the seven positives, one had a history suggestive of TDI asthma and one had a rash which may have been TDI related. These results indicate that false positive RAST with TMI-HSA may occur in asymptomatic workers.

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