Late response in exercise-induced asthma


Dr C. R. Horn. Department of Respiratory Medicine. Guy's Hospital. London SE1 9RT.


Eight subjects induced bronchospasm by free-range running. Four of these demonstrated a hue response at 5-6 hr after exercise. When compared lo the other group of four subjects, who also developed an early response but no late response, the difference in FEV1 at 5-6 hr was highly statistically significant. Although the phenomenon is not universally manifest it should no longer be held that there is no late response in exercise-induced asthma.