Tests for allergy to housedust
Article first published online: 27 APR 2006
Clinical & Experimental Allergy
Volume 14, Issue 4, pages 319–327, July 1984
How to Cite
GUERIN, B., LELIEVRE, D., PELLEGRIN, A., LEYNADIER, F., LEBEL, B., DRY, J. and HEWITT, B. E. (1984), Tests for allergy to housedust. Clinical & Experimental Allergy, 14: 319–327. doi: 10.1111/j.1365-2222.1984.tb02212.x
- Issue published online: 27 APR 2006
- Article first published online: 27 APR 2006
- (Received 12 July 1982; revised text accepted 22 March 1983)
In an attempt to find a satisfactory combination of method and antigen extract for tests of hypersensitivity to housedust, variations of skin test, RAST, histamine release and basophil degranulation tests have been used to test efficacy of five commonly used extracts of housedust or its components.
The Lincoln Multitest for skin prick tests in its present form induced too much trauma for type-I hypersensitivity tests, though it has advantages for comparison of several extracts. Histamine release and two versions of basophil degranulation tests all gave good results but not consistently. RAST gave the best correlation between all extracts, but neither the in vivo nor in vitro tests gave perfect concordance with sensitivity in all patients and all extracts.