A controlled trial of oral hyposensitization in pollen asthma and rhinitis in children
Article first published online: 27 APR 2006
Clinical & Experimental Allergy
Volume 14, Issue 6, pages 541–550, November 1984
How to Cite
COOPER, P. J., DARBYSHIRE, J., NUNN, A. J. and WARNER, J. O. (1984), A controlled trial of oral hyposensitization in pollen asthma and rhinitis in children. Clinical & Experimental Allergy, 14: 541–550. doi: 10.1111/j.1365-2222.1984.tb02242.x
- Issue published online: 27 APR 2006
- Article first published online: 27 APR 2006
- (Received 8 October 1983; accepted for publication 31 October 1983)
This study describes the effect of an orally administered grass-pollen vaccine, taken pre-seasonally, on the clinical symptoms of fifty-four children with hay fever, asthma or both, during the 1982 grass-pollen season.
Oral mixed grass-pollen vaccine and a matched placebo were randomly allocated to form two matched groups. Although small differences were observed in favour of the active group for both hay fever and asthma, no significant advantage was demonstrated over placebo in terms of symptom scores or additional medication required.