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Clinical & Experimental Allergy

Monitoring of maximum expiratory peak flow rates and histamine inhalation tests in the investigation of occupational asthma


Dr André Cartier, Department of Chest Medicine, Hôpital du Sacré-Coeur, 5400 W. Gouin Blvd, Montreal H4J 1C5, Canada.


A 49 year old carpenter developed asthma after he was employed in a new workshop. Specific inhalation tests carried out in a laboratory with presswood sawdust and the different glues used at work were negative. Monitoring peak expiratory flow rates (PEFR) at work revealed a progressive fall on consecutive days with recovery after periods off-work. Histamine inhalation tests showed a definite increase in bronchial hyperexcitability after working periods. Monitoring of PEFR in conjunction with histamine inhalation tests can thus help in confirming occupational asthma.

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