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IgE and IgG4 antibodies to bovine milk fat globule membrane in atopic eczema patients: a study of their occurrence, relevance and antigenic specificity
Article first published online: 27 APR 2006
DOI: 10.1111/j.1365-2222.1985.tb02284.x
1365-2222/asset/cover.gif?v=1&s=363d6ac7042b7535760df61b7393fd8e0a08e85f "Clinical & Experimental Allergy")
Additional Information
How to Cite
SHAKIB, F., BROWN, H. M., REDHEAD, R. and PHELPS, A. (1985), IgE and IgG4 antibodies to bovine milk fat globule membrane in atopic eczema patients: a study of their occurrence, relevance and antigenic specificity. Clinical & Experimental Allergy, 15: 265–271. doi: 10.1111/j.1365-2222.1985.tb02284.x
Publication History
- Issue published online: 27 APR 2006
- Article first published online: 27 APR 2006
- (Received in original form 20 July 1984 and in revised form 17 December 1984; accepted for publication 7 January 1985)
- Abstract
- References
- Cited By
Summary
IgE and IgG4 antibodies to bovine milk fat globule membrane (FGM) were measured in atopic eczema patients to determine whether their presence would account for allergy to milk in cases where whole or individual milk protein-specific antibodies are not detectable. The study demonstrates that the measurements of IgE and IgG4 antibodies to FGM do not offer any additional diagnostic value in milk exacerbated cases of atopic eczema. Furthermore, cross-inhibition studies with four milk proteins showed that these FGM-reactive IgE and IgG4 antibodies are directed against α-casein.