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Clinical & Experimental Allergy

Reaginic allergy to Parthenium pollen: evaluation by skin test and RAST

Authors

  • M. RAO,

    1. Allergy and Applied Immunology Laboratory, Department of Biochemistry, Indian Institute of Science, Bangalore-560 012, India
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    • *

      Department of Immunology, School of Public Health and Hygiene, Johns Hopkins University, Baltimore, MD-21205, U.S.A.

  • O. PRAKASH,

    1. Allergy and Applied Immunology Laboratory, Department of Biochemistry, Indian Institute of Science, Bangalore-560 012, India
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    • St. Martha's Hospital, Bangalore-560 001, India.

  • P. V. SUBBA RAO

    Corresponding author
    1. Allergy and Applied Immunology Laboratory, Department of Biochemistry, Indian Institute of Science, Bangalore-560 012, India
      Dr P. V. Subba Rao, Allergy & Applied Immunology Laboratory, Department of Biochemistry, Indian Institute of Science, Bangalore-560 012, India.
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Dr P. V. Subba Rao, Allergy & Applied Immunology Laboratory, Department of Biochemistry, Indian Institute of Science, Bangalore-560 012, India.

Summary

The pollen of Parthenium hysterophorus, an alien weed growing wild in India was found to be a potential source of allergic rhinitis. A clinical survey showed that 34% of the patients suffering from rhinitis and 12% suffering from bronchial asthma gave positive skin-prick test reactions to Parthenium pollen antigen extracts. Parthenium-specific IgE was detected in the sera of sixteen out of twenty-four patients suffering from seasonal rhinitis. There was 66% correlation between skin test and RAST.

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