Anaphylaxis produced by rubber glove contact. Case reports and immunological identification of the antigens involved
Article first published online: 27 APR 2006
Clinical & Experimental Allergy
Volume 19, Issue 4, pages 425–430, July 1989
How to Cite
MORALES, C., BASOMBA, A., CARREIRA, J. and SASTRE, A. (1989), Anaphylaxis produced by rubber glove contact. Case reports and immunological identification of the antigens involved. Clinical & Experimental Allergy, 19: 425–430. doi: 10.1111/j.1365-2222.1989.tb02409.x
- Issue published online: 27 APR 2006
- Article first published online: 27 APR 2006
- Submitted 19 July 1988; revised 4 January 1989; accepted 11 January 1989.
A study was carried out on six subjects suffering from anaphylactic reactions including asthma, rhinoconjunctivitis, contact urticaria and hypotension following contact with rubber gloves. All of them showed skin sensitivity and serum specific IgE to various preparations of natural latex, and not to other chemicals used in glove manufacturing. Immunoblotting techniques demonstrated that at least four soluble polypeptides from natural latex had the ability to bind specific human IgE. The results suggested that natural latex proteins present in rubber gloves can cause severe specific hypersensitivity reactions.