Members: P. Maestrelli (chairman), University of Padova, Italy; X. Baur, University of Bochum, Germany; J. C. Bessot, Service de Pneumologie, Strasbourg, France; A. Cirla, Ospedale di Cremona, Italy; P. Gervais, Hôpital Fernand-Widal, Paris, France; J. Godnic-Cvar, University of Zagreb, Yugoslavia; L. Leonhardt, Klinisches Institut für Allergien und Atemwegserkrankungen, Hannover, West Germany; F. Madsen, Bispebjerg Hospital, Copenhagen, Denmark; G. Moscato, IRC Clinica del Lavoro Foundation, Medical Center of Pavia, Italy; A. J. Newman Taylor, Brompton Hospital, London, U.K.; E. Zuskin, School of Public Health, Zagreb, Yugoslavia.
Guidelines for the diagnosis of occupational asthma
Subcommittee on ‘Occupational Allergy’ of the European Academy of Allergology and Clinical Immunology*
Article first published online: 27 APR 2006
Clinical & Experimental Allergy
Volume 22, Issue 1, pages 103–108, January 1992
How to Cite
(1992), Guidelines for the diagnosis of occupational asthma. Clinical & Experimental Allergy, 22: 103–108. doi: 10.1111/j.1365-2222.1992.tb00121.x
- Issue published online: 27 APR 2006
- Article first published online: 27 APR 2006
- Received 4 December 1990; revised 22 July 1991; accepted 26 July 1991.
The ‘Guidelines for the diagnosis of Occupational Asthma’ have been written by the Subcommittee on Occupational Allergy of the European Academy of Allergology and Clinical Immunology to give common diagnostic criteria in the evaluation of individual patients with suspected occupational asthma. The suggested diagnostic procedure includes five steps.
History suggestive of occupational asthma.
Confirmation of bronchial asthma, with demonstration of reversibility of bronchial obstruction, of non-specific bronchial hyperreactivity and of increased diurnal variability of peak expiratory flow rates (PEFR).
Confirmation of work-related bronchoconstriction with serial measurements of PEFR and of non-specific bronchial reactivity.
Confirmation of sensitization to occupational agents with skin tests and/or in vitro tests to detect specific immunoglobulins.
Confirmation of causal role of occupational agent with specific bronchial challenges.
Requirements, advantages and limitations are discussed for each of the suggested techniques.