Supported by the Deutsche Forschungsgemeinschaft (SFB 174, A 11)
How allergenic are hypoallergenic infant formulae?
Article first published online: 27 APR 2006
Clinical & Experimental Allergy
Volume 22, Issue 6, pages 635–639, June 1992
How to Cite
RUGO, E., WAHL, R. and WAHN, U. (1992), How allergenic are hypoallergenic infant formulae?. Clinical & Experimental Allergy, 22: 635–639. doi: 10.1111/j.1365-2222.1992.tb00180.x
- Issue published online: 27 APR 2006
- Article first published online: 27 APR 2006
- Submitted 29 August 1991; revised 3 December 1991; accepted 13 December 1991.
In a comparative study six different protein hydrolysates, marketed as ‘hypoallergenic’ infant formulae were investigated by skin prick tests, RAST, RAST inhibition and titrated provocation tests. Whey hydrolysates containing a high percentage of larger peptides were found to have the highest capacity to induce positive skin tests, provocation tests and. To bind to human serum IgE antibodies of cow's milk allergic children. Casein hydrolysates appeared to have the least residual allergenic activity. We recommend that ‘hypoallergenic’ formulae should be tested in each case, before being prescribed to cow's milk sensitive children.