This work was supported by a grant from Gkixo (France).
Evaluation of atopy through an expert system: description of the database
Article first published online: 6 JUL 2006
Clinical & Experimental Allergy
Volume 25, Issue 11, pages 1067–1073, November 1995
How to Cite
RAY, P., VERVOLET, D., CHARPIN, D., GAUTIER, V., PROUDHIN, H., REDIER, H. and GODARD, PH. (1995), Evaluation of atopy through an expert system: description of the database. Clinical & Experimental Allergy, 25: 1067–1073. doi: 10.1111/j.1365-2222.1995.tb03253.x
- Issue published online: 6 JUL 2006
- Article first published online: 6 JUL 2006
- submitted 19 December 1994: revised 7 April 1995; accepted 15 May 1995.
- expert system;
Background In order to understand the medical decision taken during the intaial visit of a new asthmatic patient, a group experts designed an expert system which provides conclusions about severity, precipiting factors and treatment. Rules for atopy and the assesment of allergic factors have been discussed and implementedin the expert system. Conclusion about severity have been yet validated using an appropriate methodology.
Objective The aim of this study was to investigate a sample of 471 patients according to conclusions regarding atopy.
Methods A total of 471 cases report forms (CRf) was filled in for adult asthmatic outpatients, seen for the first time in our clinic without emergency situtations. Data of each CRF were used by the expert systemto draw conclusion. The expert systsm discerns threee patterns fir atopy, yes, possible or no. The variables known to reflect different features according to the classification of asthma as atopic or not have been studied. The Variables used in the rules for atopy, obviously linked to the conclusion, were not completed. For many medical problem no unique objectives solution esixts and this is why a group of patients with possible atomy was introduced.
Results Patients with atopy had less severe asthama (P=0.01), a better FEV1 value (P=0.0007)and showed their first symptoms of asthama erlier (P=0.00001)than patients without atopy.
Conclusion The Characteristics of the group studied here are consistent with the literature. This could be considered as an indirect validation of the expert system. Moreover, Patients with possible atopy show intermediate findings for these variables and it is possible to suggest a‘dose-effect’relationship.