Buckwheat flour hypersensitivity: an occupational asthma in a noodle maker
Article first published online: 27 APR 2006
Clinical & Experimental Allergy
Volume 26, Issue 4, pages 423–427, April 1996
How to Cite
PARK, H.-S. and NAHM, D.-H. (1996), Buckwheat flour hypersensitivity: an occupational asthma in a noodle maker. Clinical & Experimental Allergy, 26: 423–427. doi: 10.1111/j.1365-2222.1996.tb00558.x
- Issue published online: 27 APR 2006
- Article first published online: 27 APR 2006
- Submitted 18 July 1995; revised 4 September 1995; accepted 20 October 1995.
- occupational allergy;
- buckwheat flour
Background There have been very few reports of occupationai allergies caused by inhalation of buckwheat flour. In this paper, we present a case of occupational asthma and rhinitis caused by buckwheat flour inhalation.
Methods and results The patient had strong positive responses to grass and ragweed poiiens as well. The bronchoprovocation test showed early asthmatic response to buckwheat flour extracts. Serum specific IgE antibody to buckwheat flour was detected by enzyme-linked immunosorbent assay (ELISA). In order to further identify the allergenic component of the extracts, sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) and electroblotting studies were performed. Eight IgE binding components (9–55 kDa) were detected within the buckwheat flour extracts.
Conclusion These results suggest that inhalation of buckwheat flour can caused IgE mediated bronchoconstriction.