Association of childhood perennial allergic rhinitis with subclinical airflow limitation
Article first published online: 23 NOV 2009
© 2009 Blackwell Publishing Ltd
Clinical & Experimental Allergy
Volume 40, Issue 3, pages 398–402, March 2010
How to Cite
Ciprandi, G. and Capasso, M. (2010), Association of childhood perennial allergic rhinitis with subclinical airflow limitation. Clinical & Experimental Allergy, 40: 398–402. doi: 10.1111/j.1365-2222.2009.03399.x
- Issue published online: 8 FEB 2010
- Article first published online: 23 NOV 2009
- Submitted 30 June 2009; revised 10 September 2009; accepted 14 September 2009
- allergic rhinitis;
- mite sensitization;
Background Allergic rhinitis (AR) is a relevant risk factor for the onset of asthma, and a close association exists between the nose and the bronchi. Recently, it has been evidenced that the duration of AR and mite allergy represent high risks for spirometric impairment in allergic adults.
Aim To evaluate a group of AR children, without bronchial symptoms, to investigate spirometric impairments.
Methods Two hundred children with moderate-severe AR were consecutively evaluated. Clinical examination, skin prick test, and spirometry were performed in all children.
Results Thirty-one percent of the children had forced expiratory flow at 25% and 75% of the pulmonary volume (FEF25–75%)<80% of the predicted values and 11% had both forced expiratory volume in 1 s and FEF25–75%<80% of the predicted values. Rhinitis duration and sensitization to house dust mites were significantly associated with impaired values of these spirometric parameters.
Conclusion This study highlights the close link between the upper and the lower airways and the role of some risk factors, such as long duration and mite sensitization, as early prognostic markers of bronchial involvement in children with ARand perceiving nasal symptoms alone.
Cite this as: G. Ciprandi and M. Capasso, Clinical & Experimental Allergy, 2010 (40) 398–402.