Dendritic cell and T cell responses in children with food allergy
Version of Record online: 5 SEP 2010
© 2010 Blackwell Publishing Ltd
Clinical & Experimental Allergy
Volume 41, Issue 1, pages 61–71, January 2011
How to Cite
Frischmeyer-Guerrerio, P. A., Guerrerio, A. L., Chichester, K. L., Bieneman, A. P., Hamilton, R. A., Wood, R. A. and Schroeder, J. T. (2011), Dendritic cell and T cell responses in children with food allergy. Clinical & Experimental Allergy, 41: 61–71. doi: 10.1111/j.1365-2222.2010.03606.x
- Issue online: 14 DEC 2010
- Version of Record online: 5 SEP 2010
- Submitted 29 April 2010; revised 10 June 2010; accepted 20 July 2010.
Table S1. Changes in cytokine secretion with milk stimulation. P values comparing difference in cytokine levels produced by pDCs or mDCs co-cultured with CD4+ T cells in the presence or absence of 10 μg/mL milk extract using Wilcoxon Matched-Pairs Signed-Ranks Test.
Fig. S1. Spearman correlation was used to compare the levels of TNF-α, IL-6, IL-10, and GM-CSF produced by pDCs or mDCs following treatment with an anti-IgE crosslinking stimulus to the level of expression of FcɛRI on the respective DC subtype. Statistically significant relationships are noted.
Fig. S2. Cytokine secretion by DC-CD4+ T cell co-cultures. pDCs or mDCs from FA, CON, and EE subjects were cultured together with autologous CD4+ T cells in media alone or 50 μg/mL of crude milk extract. Indicated cytokines (pg/mL) were measured 96 hours after stimulation.
Fig. S3. Expression (mean fluorescence intensity; MFI) of FcɛRIα on pDCs and mDCs from FA, CON, and EE subjects.
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