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Original Article
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A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness
Article first published online: 22 AUG 2011
DOI: 10.1111/j.1365-2222.2011.03840.x
© 2011 Blackwell Publishing Ltd
1365-2222/asset/cover.gif?v=1&s=363d6ac7042b7535760df61b7393fd8e0a08e85f "Clinical & Experimental Allergy")
Additional Information
How to Cite
Publication History
- Issue published online: 27 DEC 2011
- Article first published online: 22 AUG 2011
- Manuscript Accepted: 28 JUN 2011
- Manuscript Revised: 24 JUN 2011
- Manuscript Received: 27 OCT 2010
Funded by
- National Institutes of Health. Grant Numbers: AI077439, HL095372
References
- 1. Pathogenesis of asthma. Clin Exp Allergy 2008; 38:872–97.
- 2, , et al. Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc Natl Acad Sci USA 2007; 104:15858–63.
- 3, , et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med 2009; 180:388–95.
- 4, , et al. A novel in vivo model to study endochondral bone formation; HIF-1alpha activation and BMP expression. Bone 2007; 40:409–18.
- 5, , et al. Immunohistochemical localization of periostin in tooth and its surrounding tissues in mouse mandibles during development. Anat Rec A Discov Mol Cell Evol Biol 2004; 281:1264–75.
- 6, , et al. Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart. Circ Res 2008; 102:752–60.
- 7, , et al. Periostin is expressed within the developing teeth at the sites of epithelial-mesenchymal interaction. Dev Dyn 2004; 229:857–68.
- 8, , et al. Periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol 2005; 25:11131–44.
- 9, , et al. Periostin is essential for the integrity and function of the periodontal ligament during occlusal loading in mice. J Periodontol 2008; 79:1480–90.
- 10
- 11, , . The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction. J Mol Cell Cardiol 2010; 48:504–11.
- 12, , et al. Periostin is essential for cardiac healing after acute myocardial infarction. J Exp Med 2008; 205:295–303.
- 13, , et al. Incorporation of tenascin-C into the extracellular matrix by periostin underlies an extracellular meshwork architecture. J Biol Chem 2010; 285:2028–39.
- 14, , et al. Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues. J Cell Biochem 2007; 101:695–711.
- 15, , et al. Periostin mediates vascular smooth muscle cell migration through the integrins alphavbeta3 and alphavbeta5 and focal adhesion kinase (FAK) pathway. Atherosclerosis 2010; 208:358–65.
- 16, , et al. Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma. Proc Natl Acad Sci USA 2010; 107:14170–5.
- 17, , et al. In vivo disruption of TGF-beta signaling by Smad7 in airway epithelium alleviates allergic asthma but aggravates lung carcinogenesis in mouse. PLoS ONE 2010; 5:e10149.
- 18, , . Reduced expression of transforming growth factor beta 1 exacerbates pathology in an experimental asthma model. Eur J Immunol 2005; 35:198–206.
- 19, , et al. Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease. Am J Respir Crit Care Med 2007; 176:974–82.
- 20, , , , , . Smad3 -signalling and Th2 cytokines in normal mouse airways and in a mouse model of asthma. Int J Biol Sci 2007; 3:477–85.
- 21, , et al. Transforming growth factor-beta regulates house dust mite-induced allergic airway inflammation but not airway remodeling. Am J Respir Crit Care Med 2008; 177:593–603.
- 22, , et al. Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma. Proc Natl Acad Sci USA 2010; 107:5652–7.
- 23, , , , . Tgf-Beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma. PLoS ONE 2010; 5:e9674.
- 24, , et al. Strain-specific phenotypes of airway inflammation and bronchial hyperresponsiveness induced by epicutaneous allergen sensitization in BALB/c and C57BL/6 mice. Int Arch Allergy Immunol 2010; 152 (Suppl):67–74.
- 25, . Comparison of allergic lung disease in three mouse strains after systemic or mucosal sensitization with ovalbumin antigen. Immunogenetics 2009; 61:199–207.
- 26, , et al. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 2007; 447:92–6.
- 27, , , . Interleukin-5-mediated allergic airway inflammation inhibits the human surfactant protein C promoter in transgenic mice. J Biol Chem 2001; 276:8453–9.
- 28, , . ADAM33 is not essential for growth and development and does not modulate allergic asthma in mice. Mol Cell Biol 2006; 26:6950–6.
- 29, , et al. Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2. Respir Res 2004; 5:12.
- 30, , et al. Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc Natl Acad Sci USA 2010; 107:11489–94.
- 31, , et al. A novel method of gene transcript profiling in airway biopsy homogenates reveals increased expression of a Na+-K+-Cl- cotransporter (NKCC1) in asthmatic subjects. Genome Res 2001; 11:1473–83.
- 32, , , . Periostin a novel mediator of epithelial mesenchymal communication in asthma. San Diego, California:American Thoracic Society International Conference, 2009; A4271.
- 33, , et al. Conversion of peripheral CD4 + CD25- naive T cells to CD4 + CD25 + regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003; 198:1875–86.
- 34, , et al. Analysis of novel disease-related genes in bronchial asthma. Cytokine 2002; 19:287–96.
- 35, , . Genetics of airway hyperresponsiveness. J Allergy Clin Immunol 2001; 108:11–20.
- 36, , , , , . Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to Aspergillus in CCR4-/- mice. FASEB J 2002; 16:1313–15.
- 37, , et al. Enhanced pulmonary allergic responses to Aspergillus in CCR2-/- mice. J Immunol 2000; 165:2603–11.
- 38, , et al. Coexpression of TGF-beta1 and IL-10 enables regulatory T cells to completely suppress airway hyperreactivity. J Immunol 2008; 181:7751–8.
- 39, , et al. A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proc Natl Acad Sci USA 2009; 106:9099–104.
- 40, , , , , . PI3K gamma-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling. Am J Physiol Lung Cell Mol Physiol 2009; 296:L210–9.
- 41, , et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006; 441:235–8.
- 42, , et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med 2007; 204:1775–85.
- 43, , , , . IgE versus IgG4 production can be differentially regulated by IL-10. J Immunol 1998; 160:3555–61.
- 44, , , . T regulatory-1 cells induce IgG4 production by B cells: role of IL-10. J Immunol 2005; 174:4718–26.
- 45, , , , . Role of interleukin 10 in specific immunotherapy. J Clin Invest 1998; 102:98–106.
- 46, , et al. IL-10 inhibits CD28 and ICOS costimulations of T cells via src homology 2 domain-containing protein tyrosine phosphatase 1. J Allergy Clin Immunol 2007; 120:76–83.
- 47, , et al. Akdis CA, IL-10 suppresses CD2-mediated T cell activation via SHP-1. Mol Immunol 2009; 46:622–9.
- 48, , , , . A molecular basis for T cell suppression by IL-10: CD28-associated IL-10 receptor inhibits CD28 tyrosine phosphorylation and phosphatidylinositol 3-kinase binding. FASEB J 2000; 14:1666–8.
- 49, , , , . Attenuation of allergen-induced airway hyperresponsiveness is mediated by airway regulatory T cells. Am J Physiol Lung Cell Mol Physiol 2009; 296:L307–19.
- 50, . Naturally occurring and inducible T-regulatory cells modulating immune response in allergic asthma. Am J Respir Crit Care Med 2009; 180:211–25.
- 51, , et al. Naturally occurring lung CD4(+)CD25(+) T cell regulation of airway allergic responses depends on IL-10 induction of TGF-beta. J Immunol 2007; 178:1433–42.
- 52, , et al. Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses. Mucosal Immunol 2008; 1:289–96.
- 53, , et al. Periostin regulates goblet cell metaplasia in a model of allergic airway inflammation. J Immunol 2011; 186:4959–66.