Chloracne—study of an outbreak with new clinical observations


  • Presented as a paper at the 70th annual meeting of the British Association of Dermatologists, Warwick, 18–21 July 1990, and published in abstract form (British Journal of Dermatology 1990; 123 (Suppl. 37): 21).

Dr A. J. G. McDonagh, Department of Dermatology, Royal Hallamshire Hospital, Glossop Road, Sheffield SKI 2JF, UK.


A recent outbreak of chloracne in 17 workers is reported at a plant manufacturing dichloroaniline derivatives. Comedones developed 6–12 weeks after accidental exposure to the chloracnegenic contaminants and were present in every case. Cutaneous xerosis and a folliculitis, previously only rarely described as manifestations of chloracne, were noted in half the patients. The pathogenesis of these lesions is uncertain but may involve a disorder of keratinization.