Successful treatment with topical PUVA of nodular cutaneous plasmacytosis associated with alopecia of the scalp


Dr Kei Kuroda, Department of Dermatology, Chiba University, School of Medicine, 1-8-1, Inohana, Chuo-ku, Chiba City, Chiba 260, Japan.


We obtained a successful response to PUVA therapy in a 51-year-old Japanese man who had multiple nodules of the trunk, extremities and scalp along with polyclonal hypergammaglobulinaemia; the scalp lesions were associated with extensive alopecia. Examination of skin biopsies showed a dense infiltrate of mature plasma cells in the dermis and hair follicles; no systemic disease or functional involvement of other organs was detected. The clinical and histological findings were compatible with cutaneous plasmacytosis and treatment with topical PUVA gradually reduced the size and number of the lesions.