Treatment of port-wine stains with the 595-nm pulsed dye laser: a pilot study in Chinese patients

Authors

  • H. Liu,

    1. Institute of Laser Medicine and Bio-Photonics, Shanghai Jiao Tong University, Shanghai, China; *College of Life Sciences, East China Teacher's University; and †Laser Centre, Shanhai Conbio Plastic Surgery Hospital, Shanghai, China
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  • Y. Dang,

    1. Institute of Laser Medicine and Bio-Photonics, Shanghai Jiao Tong University, Shanghai, China; *College of Life Sciences, East China Teacher's University; and †Laser Centre, Shanhai Conbio Plastic Surgery Hospital, Shanghai, China
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  • X. Chai,

    1. Institute of Laser Medicine and Bio-Photonics, Shanghai Jiao Tong University, Shanghai, China; *College of Life Sciences, East China Teacher's University; and †Laser Centre, Shanhai Conbio Plastic Surgery Hospital, Shanghai, China
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  • Z. Wang,

    1. Institute of Laser Medicine and Bio-Photonics, Shanghai Jiao Tong University, Shanghai, China; *College of Life Sciences, East China Teacher's University; and †Laser Centre, Shanhai Conbio Plastic Surgery Hospital, Shanghai, China
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  • L. Ma,

    1. Institute of Laser Medicine and Bio-Photonics, Shanghai Jiao Tong University, Shanghai, China; *College of Life Sciences, East China Teacher's University; and †Laser Centre, Shanhai Conbio Plastic Surgery Hospital, Shanghai, China
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  • Q. Ren

    1. Institute of Laser Medicine and Bio-Photonics, Shanghai Jiao Tong University, Shanghai, China; *College of Life Sciences, East China Teacher's University; and †Laser Centre, Shanhai Conbio Plastic Surgery Hospital, Shanghai, China
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  • Conflict of interest: none declared. The first two authors contributed equally to this work.

Dr Qiushi Ren, Room 406, Biology Building 2, 800 Dongchuan Road, 200240, Shanghai, PR China. E-mail: renqsh@sjtu.edu.cn

Summary

The 595-nm pulsed dye laser (PDL) is one of the newest developments in the treatment for port-wine stains (PWS). The aim of this study was to investigate the effectiveness of the treatment of PWS in Chinese patients using the 595-nm PDL. In total, 184 patients with PWS over the face, neck and trunk or limbs were enrolled in the study. All the patients were treated with the 595-nm PDL 3–6 times, with a 4-week interval between each treatment. Treatment parameters varied for each patient according to the colour and location of the PWS. The efficacy of treatments and any side-effects were evaluated. Results were graded as percentage resolution (0–25%, 25–50%, 50–75% and 75–100%). Of the 184 patients who completed the study, 115 (62.5%) achieved excellent improvement, 38 (20.7%) achieved good results, and 31 (16.8%) had an unsatisfactory outcome (moderate and poor response). We found > 75% improvement for 76% of facial PWS (95/125), 43% of neck PWS and 20.8% of trunk or limb PWS. Pain and topical erythema were commonly reported immediately after the laser treatments. Prominent hyperpigmentation occurred in only 11 cases (6.0%) with poor improvement, and resolved within 6 months. The 595-nm PDL appears to be safe, effective and well tolerated in the treatment of PWS in Chinese patients.

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