Conflict of interest: none declared.
Lupus vulgaris at the site of BCG vaccination: report of three cases
Version of Record online: 15 DEC 2008
© 2008 The Author(s). Journal compilation © 2008 British Association of Dermatologists
Clinical and Experimental Dermatology
Volume 34, Issue 5, pages e167–e169, July 2009
How to Cite
Farsinejad, K., Daneshpazhooh, M., Sairafi, H., Barzegar, M. and Mortazavizadeh, M. (2009), Lupus vulgaris at the site of BCG vaccination: report of three cases. Clinical and Experimental Dermatology, 34: e167–e169. doi: 10.1111/j.1365-2230.2008.03041.x
- Issue online: 1 JUN 2009
- Version of Record online: 15 DEC 2008
- Accepted for publication 16 May 2008
Lupus vulgaris (LV) is a rare complication of the bacille Calmette–Guérin (BCG) vaccination, and about 65 cases of inoculation tuberculosis resembling LV have been reported in the literature. We report three cases of LV, developing many years later at the inoculation site of BCG vaccine. All three cases had a single BCG vaccination, with a LV lesion at or in the vicinity of the vaccination site, a strong positive Mantoux test, noncaseating granuloma histologically, and two of the patients had a positive PCR result for mycobacterial complex. One of the patients had an unusually delayed appearance of the LV lesion, after an interval of about 17 years, and another case was remarkable because of the large size of the lesion (210 × 110 mm).