Conflict of interest: none declared.
Hypereosinophilic syndrome in an atopic patient
Article first published online: 17 JUN 2009
© 2009 The Author(s). Journal compilation © 2009 British Association of Dermatologists
Clinical and Experimental Dermatology
Volume 34, Issue 8, pages e643–e646, December 2009
How to Cite
Neve, S., Beukers, S. and Kirtschig, G. (2009), Hypereosinophilic syndrome in an atopic patient. Clinical and Experimental Dermatology, 34: e643–e646. doi: 10.1111/j.1365-2230.2009.03356.x
- Issue published online: 13 NOV 2009
- Article first published online: 17 JUN 2009
- Accepted for publication 6 November 2008
Hypereosinophilic syndrome (HES) is a rare, heterogeneous group of systemic diseases characterized by sustained overproduction of eosinophils leading to variable end-organ damage. The skin is affected in 45–60% of patients and may be of diagnostic and prognostic value. In 1975, three criteria were suggested for the diagnosis of HES: (i) blood eosinophilia of > 1.5 × 109/L present for > 6 months, (ii) no apparent cause for the hypereosinophilia, and (iii) signs of end-organ dysfunction. We present a patient with hypereosinophilia in whom a delay in diagnosing HES occurred, partly due to his atopic constitution. However, atopy is not associated with such high or longstanding eosinophilia.