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Acquired perforating dermatosis associated with pregnancy


  • Conflict of interest: none declared.

Dr Rachel Healy, Department of Dermatology, The Royal London Hospital, Whitechapel, London E1 1BB, UK


Acquired perforating collagenosis (APC) is a rare condition in which altered collagen and elastin fibres undergo transepidermal elimination. The pathogenesis is unknown but it is usually associated with underlying systemic disease, most commonly diabetes mellitus and renal impairment. We describe a case of an acquired perforating disorder occurring in pregnancy. APC is a diagnosis that can easily be missed, especially in atypical cases such as ours, and clinicians and histopathologists need to be aware of this condition to avoid unnecessary patient morbidity.