Conflict of interest: none declared.
Clinical dermatology • Concise report
Generalized granuloma annulare with open comedones in photoexposed areas
Article first published online: 11 MAR 2011
© The Author(s). CED © 2011 British Association of Dermatologists
Clinical and Experimental Dermatology
Volume 36, Issue 5, pages 495–498, July 2011
How to Cite
Bhushan, P., Aggarwal, A., Yadav, R. and Baliyan, V. (2011), Generalized granuloma annulare with open comedones in photoexposed areas. Clinical and Experimental Dermatology, 36: 495–498. doi: 10.1111/j.1365-2230.2011.04025.x
- Issue published online: 17 JUN 2011
- Article first published online: 11 MAR 2011
- Accepted for publication 13 November 2010
Granuloma annulare (GA) is a noninfectious necrobiotic granuloma, which can present as localized or generalized patterns. We present a case of generalized GA with multiple large open comedones over the lesions in a woman with hypothyroidism and diabetes mellitus. GA is associated with collagen and elastic-fibre damage, which may lead to loss of follicular support and resultant open comedone formation, analogous to solar elastosis or senile comedones. The rapid recovery of our patient after treatment with of oral hypoglycaemics supports the role of insulin resistance as a predisposing factor for GA.