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Scleromyxoedema with disseminated subcutaneous nodules: rare presentation of an uncommon dermatosis


  • Conflict of interest: none declared.

Dr Amrinder J. Kanwar, Department of Dermatology, Venereology and Leprology, Postgradaute Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India


Scleromyxoedema, also known as generalized lichen myxoedematosus, is a cutaneous mucinosis characterized by a generalized papular and sclerodermoid eruption, mucin deposition, increased fibroblast proliferation and fibrosis. It is often associated with underlying monoclonal gammopathy, and it responds poorly to treatment. There are very few reports of nodular eruption in scleromyxoedema. We report a case of a prominent nodular eruption in an adolescent boy with scleromyxoedema without any underlying paraproteinaemia, and review the literature.