Conflict of interest: none declared.
Sarcoid and the nail: review of the literature
Article first published online: 1 FEB 2013
© The Author(s). CED © 2013 British Association of Dermatologists
Clinical and Experimental Dermatology
Volume 38, Issue 2, pages 119–125, March 2013
How to Cite
Momen, S. E. and Al-Niaimi, F. (2013), Sarcoid and the nail: review of the literature. Clinical and Experimental Dermatology, 38: 119–125. doi: 10.1111/j.1365-2230.2012.04470.x
- Issue published online: 12 FEB 2013
- Article first published online: 1 FEB 2013
- Accepted for publication 19 May 2012
Nail involvement in sarcoidosis is rare, but its presence is often associated with chronic systemic disease. We have reviewed all 33 reported cases of nail involvement with sarcoidosis, including our own case. Nail changes in sarcoidosis, while rare, can include dystrophy (n = 10, 30%), onycholysis (n = 7, 21%), subungual hyperkeratosis (n = 7, 21%), nail hyperkeratosis (n = 2, 6%) and longitudinal ridging (n = 8, 24%). All reported cases of nail sarcoidosis occurred in the setting of systemic involvement. In almost half of the cases, bony cysts were noted on radiological examination. The presence of nail dystrophy in a patient with sarcoidosis should therefore prompt radiological examination and investigation for systemic involvement.