SEARCH

SEARCH BY CITATION

References

  • 1
    Weis M , von Scheidt W . Cardiac allograft vasculopathy: a review . Circulation 1997 ; 96 : 206977 .
  • 2
    Springer TA . Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration . Annu Rev Physiol 1995 ; 57 : 82772 .
  • 3
    Flach R , Spieled N , Flohe S et al. Analysis of intragraft cytokine expression during early reperfusion after liver transplantation using semi-quantitative RT-PCR . Cytokine 1998 ; 10 : 44551 .
  • 4
    Gu L , Tseng S , Horner RM et al. Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1 . Nature 2000 ; 404 : 40711 .
  • 5
    Murphy PM , Baggiolini M , Charo IF et al. International Union of Pharmacology, XXII: nomenclature for chemokine receptors . Pharmacol Rev 2000 ; 52 : 14576 .
  • 6
    Luster AD . Chemokines: chemotactic cytokines that mediate inflammation . N Engl J Med 1998 ; 338 : 43645 .
  • 7
    Gao W , Faia KL , Csizmadia V et al. Beneficial effects of targeting CCR5 in allograft recipients . Transplantation 2001 ; 72 : 1199205 .
  • 8
    Heredia A , Amoroso A , Davis C et al. Rapamycin causes down-regulation of CCR5 and accumulation of anti-HIV beta-chemokines: an approach to suppress R5 strains of HIV-1 . Proc Natl Acad Sci USA 2003 ; 100 : 10411 .
  • 9
    Sho M , Sandner SE , Najafian N et al. New insights into the interactions between T-cell costimulatory blockade and conventional immunosuppressive drugs . Ann Surg 2002 ; 236 : 66775 .
  • 10
    Li Y , Li XC , Zheng XX et al. Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance . Nat Med 1999 ; 5 : 1298302 .
  • 11
    Corry RJ , Winn HJ , Russell PS . Primarily vascularized allografts of hearts in mice: the role of H-2D, H-2K, and non-H-2 antigens in rejection . Transplantation 1973 ; 16 : 34350 .
  • 12
    Karim M , Kingsley CI , Bushell AR , Sawitzki BS , Wood KJ . Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25+CD4+precursors in a thymus-independent process . J Immunol 2004 ; 172 : 9238 .
  • 13
    Hubeau C , Apostolou I , Kobzik L . Targeting of CD25 and glucocorticoid induced TNF receptor family-related gene-expressing T cells differentially modulates asthma risk in offspring of asthmatic and normal mother mice . J Immunol 2007 ; 178 : 147787 .
  • 14
    Gabriel TS , Sam B , George RH et al. Combined CXCR3/CCR5 blockade atternuate acute and chronic rejection . J Immunol 2008 ; 180 : 471421 .
  • 15
    Yan L , Yan C , Fing QL et al. Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation . Transplant Int 2008 ; 21 : 48394 .
  • 16
    Eng CP , Gullo-Brown J , Chang JY , Sehgal SN . Inhibition of skin graft rejection in mice by rapamycin: a novel immunosuppressive macrolide . Transplant Proc 1991 ; 23 : 8689 .
  • 17
    Sho M , Yamada A , Najafia N . et al. Physiological mechanisms of regulating alloimmunity: cytokines, CTLA-4, CD25+ cells, and the alloreactive T cell clone size . J Immunol 2002 ; 169 : 374451 .
  • 18
    Yun JJ , Whiting D , Fischbein MP et al. Combined blockade of the chemokine receptors CCR1 and CCR5 attenuates chronic rejection . Circulation 2004 ; 109 : 9327 .
  • 19
    Yin R , Zhu J , Shao H et al. Inhibition of chemokine receptor CCR2 and CCR5 expression contributes to simvastatin-induced attenuation of cardiac allograft vasculopathy . J Heart Lung Transplant 2007 ; 26 : 48593 .
  • 20
    Akashi S , Sho M , Kashizuka H et al. A novel small-molecule compound targeting CCR5 and CXCR3 prevents acute and chronic allograft rejection . Transplantation 2005 ; 80 : 37884 .
  • 21
    Sinha SS , Pham MX , Vagelos RH et al. Effect of rapamycin therapy on coronary artery physiology early after cardiac transplantation . Am Heart J 2008 ; 889 : e16 .
  • 22
    Raichlin E , Chandrasekaran K , Kremers WK et al. Sirolimus as primary immunosuppressant reduces left ventricular mass and improves diastolic function of the cardiac allograft . Transplantation 2008 ; 86 : 1395 .
  • 23
    Kingsley CI , Nadig SN , Wood KJ . Transplantation tolerance: lessons from experimental rodent models . Transplant Int 2007 ; 20 : 82841 .
  • 24
    Groux H , O'Garra A , Bigler M et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis . Nature 1997 ; 389 : 73742 .
  • 25
    Hall BM , Pearce NW , Gurley KE , Dorsch SE . Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine: III. Further characterization of the CD4+ suppressor cells and its mechanism of action . J Exp Med 1990 ; 171 : 14157 .
  • 26
    Graca L , Thompson S , Lin CY , Adams E , Cobbold SP , Waldmann H . Both CD4+CD25+ and CD4+CD25+ regulatory cells mediate dominant transplantation tolerance . J Immunol 2002 ; 168 : 555865 .
  • 27
    Kingsley CI , Karim M , Bushell A , Wood KJ . CD4+CD25+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses . J Immunol 2002 ; 168 : 10806 .
  • 28
    Sakaguchi S , Sakaguchi N , Asano M , Itoh M , Toda M . Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases . J Immunol 1995 ; 155 : 115164 .
  • 29
    Schenk S , Kish DD , He C et al. Alloreactive T cell responses and acute rejection of single class II MHC-disparate heart allografts are under strict regulation by CD4+CD25+ T cells . J Immunol 2005 ; 174 : 37418 .
  • 30
    Kopf H , de la Rosa GM , Howard OM , Chen X . Rapamycin inhibits differentiation of Th17 cells and promotes generation of Foxp3+ T regulatory cells . Int Immunopharmacol 2007 ; 15 : 181924 .
  • 31
    Qu Y , Zhang B , Zhao L et al. The effect of immunosuppressive drug rapamycin on regulatory CD4+CD25+Foxp3+ T cells in mice . Transplant Immunol 2007 ; 17 : 15361 .
  • 32
    Battaglia M , Stabilini A , Roncarolo MG . Rapamycin selectively expands CD4+CD25+Foxp3+ regulatory T cells . Blood 2005 ; 105 : 47438 .
  • 33
    Dallman MJ , Larsen CP , Morris PJ . Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction . J Exp Med 1991 ; 174 : 4936 .
  • 34
    Saiura A , Mataki C , Murakami T et al. A comparison of gene expression in murine cardiac allografts and isografts by means of DNA microarray analysis . Transplantation 2001 ; 72 : 3209 .
  • 35
    Nagano H , Mitchell RN , Taylor MK et al. Interferon-γ deficiency prevents coronary arteriosclerosis but not myocardial rejection in transplanted mouse hearts . J Clin Invest 1997 ; 100 : 5507 .
  • 36
    Tellides G , Tereb DA , Kirkiles-Smith NC et al. Interferon-γ elicits arteriosclerosis in the absence of leukocytes . Nature 2000 ; 403 : 20711 .
  • 37
    Koh KP , Wang Y , Yi T et al. T cell-mediated vascular dysfunction of human allografts results from IFN-gamma dysregulation of NO synthase . J Clin Invest 2004 ; 114 : 84656 .
  • 38
    Wysocki CA , Jiang Q , Panoskaltsis M et al. Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease . Blood 2005 ; 106 : 33007 .
  • 39
    Yates SF , Paterson AM , Nolan KF et al. Induction of regulatory T cells and dominant tolerance by dendritic cells incapable of full activation . J Immunol 2007 ; 179 : 96776 .
  • 40
    Geijtenbeek TBH , van Vliet SJ , Engering A , 't Hart BA , van Kooyk Y . Self- and nonself-recognition by C-type lectins on dendritic cells . Annu Rev Immunol 2004 ; 22 : 3354 .
  • 41
    Schröder C , Pierson RN III , Nguyen BN et al. CCR5 blockade modulates inflammation and alloimmunity in primates . J Immunol 2007 ; 179 : 228999 .
  • 42
    Luster AD . Chemokines: chemotactic cytokines that mediate inflammation . N Engl J Med 1998 ; 338 : 43645 .
  • 43
    Sozzni S , Allavena P , D'Amico G et al. Cutting edge: differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties . J Immunol 1998 ; 161 : 10836 .
  • 44
    Sallusto F , Schaerli P , Loetscher P et al. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation . Eur J Immunol 1998 ; 28 : 27609 .