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References

  • Adachi, K. & Kano, M. (1970) Adenyl cyclase in human hair follicles. Its inhibition by dihydrotestosterone. Biochemical & Biophysical Research Communication, 41, 884890.
  • Anderson, D.C. (1974) Sex hormone binding globulin. Clinical Endocrinology, 3, 6996.
  • Aristotle (1910) The works of Aristotle (ed. J. A.Smith & W. D.Ross), Volume 4. Historia Animalium. Translated by D'ArcyThompson, Clarendon Press, Oxford .
  • Auber, L. (1952) The anatomy of follicles producing wool-fibres, with special reference to keratinization. Transactions of the Royal Society of Edinburgh, 62, 191254.
  • Baden, H.P., Grassi, A. & Kuedar, J. (1989) The effect of the drug minoxidil on hair growth. In The Biology of Wool and Hair (ed. G. E.Rogers, P. J.Reis, K. A.Ward & R. C.Marshall), pp. 217226. Chapman & Hall, London .
  • Bardin, W. C. & Lipsett, M. B. (1967) Testosterone and androstene-dione blood production rates in normal women and women with idiopathic hirsutism or polycystic ovaries. Journal of Clinical Investigation, 46, 891902.
  • Barth, J.H., Cherry, C.A., Wojnarowska, F. & Dawber, R.P.R. (1991) Cyproterone acetate for severe hirsutism: results of a double-blind dose-ranging study. Clinical Endocrinology, 35, 510.
  • Bellastella, A., Criscuoco, T., Mango, A., Perrone, L., Sawisi, A.J. & Faggiano, M. (1983) Circannual rhythms of LH, FSH, testosterone, prolactin and Cortisol during puberty. Clinical Endocrinology, 19, 453459.
  • Bingham, K.D. & Shaw, D.A. (1973) The metabolism of testosterone by human male scalp skin. Journal of Endocrinology, 57, 111121.
  • Bradfield, R.B. (1971) Protein deprivation: comparative response of hair roots, serum protein and urinary nitrogen. American Journal of Clinical Nutrition, 24, 405410.
  • Bradfield, R.B., Bailey, M.A. & Cordano, J.A. (1968) Hair-root changes in Andean Indian children during marasmic kwashiorkor. Lancet, ii, 11691170.
  • Bradfield, R.B., Cordano, A. & Graham, G.G. (1969) Hair-root adaptation to marasmus in Andean Indian children. Lancet, ii, 13951397.
  • Champion, R.H. (1992) Disorders of sweat glands. In Textbook of Dermatology. Fifth edition (ed. A.Rook, D. S.Wilkinson, F. J. G.Ebling, R. H.Champion & J. L.Burton), pp. 17451762. Blackwell Scientific Publications, Oxford .
  • Chieffi, M. (1949) Effect of testosterone administration on the beard growth of elderly males. Journal of Gerontology, 4, 200204.
  • Choudhry, R., Hodgins, M.B., Van Der Kwast, T.H., Brinkmann, A.O. & Boersma, W.J.A. (1992) Localisation of androgen receptors in human skin by immunohistochemisty: implications for the hormonal regulation of hair growth, sebaceous glands and sweat glands. Journal of Endocrinology, 133, 467475.
  • Cipriani, R., Ruzza, G., Foresta, C., Veller-Fornasa, C. & Peserico, A. (1983) Sex hormone binding globulin & saliva testosterone levels in men with androgenetic alopecia. British Journal of Dermatology, 109, 249252.
  • Corenblum, B. (1987) Antiandrogen therapy for hirsutism–the North American Experience (Canada). In The Cause and Management of Hirsutism (ed. R. B.Greenblatt, V. B.Mahesh & R. D.Gambrell), pp. 161168. Parthenon Publishing Group, Cam-forth , UK .
  • Cott, H.B. (1940) Adaptive Coloration in Animals. Methuen, London .
  • Couchman, J.R. (1993) Hair follicle proteoglycans extracellular matrix containing basement membrane components. Journal of Investigative Dermatology, 101, 605645.
  • Cunha, G.R., Donjacour, A.A., Cook, P.S. Mee, S., Bigby, R.H., Higgins, S. & Sugimura, Y. (1987) The endocrinology and developmental biology of the prostate. Endocrine Reviews, 8, 338362.
  • Danforth, C.H. (1925) Hair with Special Reference to Hypertrichosis. American Medical Association, Chicago , Illinois .
  • Dawber, R.P.R., Ebling, F.J.G. & Wojnarowska, F.T. (1992) Disorders of hair. In Textbook of Dermatology. Fifth edition (ed. A.Rook. D. S.Wilkinson, F. J. G.Ebling, J. L.Burton & R. H.Champion), pp. 25332638. Blackwell Scientific Publications, Oxford .
  • De Villez, R.L.(Editor) (1988) Androgenetic Alopecia: from empiricism to knowledge. Clinics in Dermatology, 6, (4).
  • Dover, R. (1988) Cell kinetics of human hair follicle. Clinics in Dermatology, 6 (4), 3235.
  • Dry, F.W. (1926) The coat of the mouse (Mas musculus). Journal of Genetics, 16, 287340.
  • Duncan, M.J. & Goldman, B.D. (1984) Hormonal regulation of the annual folage colour cycle in the Djungarian hamster, Phodopus surgorus. II The role of prolactin. Journal of Experimental Zoology, 230, 93103.
  • Duncan, M.J. & Goldman, B.D. (1985) Physiological doses of prolactin stimulate pelage pigmentation in Djungarian hamster. American Journal of Physiology, 248, R664R667.
  • Ebling, F.J.G. (1976) Hair. Journal of Investigative Dermatology, 67, 98105.
  • Ebling, F.J.G. (1985a) The mythological evolution of nudity. Journal of Human Evolution, 14, 3341.
  • Ebling, F.J.G. (1985b) Age changes in cutaneous appendages. Journal of Applied Cosmetology, 3, 243250.
  • Ebling, F.J., Cooke, I.D., Randall, V.A., Sawers, R.S. & Skinner, J. (1980) The effects of cyproterone acetate on the human hair follicle and its associated glands. In Androgenisation in Women. (ed. J.Hammerstein, U.Lachnit-Fixson, F.Neumann & G.Plewig), pp. 239245. Excerpta Medica, Amsterdam .
  • Ebling, F.J.G. & Cunliffe, W.J. (1992) Disorders of the sebaceous glands. In Textbook of Dermatology. Fifth edition (ed. A.Rook, D. S.Wilkinson, F. J. G.Ebling, R. H.Champion & J. L.Burton), pp. 16991745. Blackwell Scientific Publications, Oxford .
  • Ebling, F.J.G., Hale, P.A. & Randall, V.A. (1991) Hormones and hair growth. In Biochemistry and Physiology of the Skin, Second edition (ed L. A.Goldsmith), Clarenden Press, Oxford .
  • Ebling, F.J.G. & Hervey, G.R. (1964) The activity of hair follicles in parabiotic rats. Journal of Embryology and Experimental Morphology, 12, 425438.
  • Ebling, F.J.G. & Johnson, E. (1959) Hair growth and its relation to vascular supply in rotated skin grafts and transposed flaps in the albino rat. Journal of Embryology and Experimental Morphology, 7, 417430.
  • Ebling, F.J.G. & Johnson, E. (1961) Systemic influence on activity of hair follicles in skin homografts. Journal of Embryology and Experimental Morphology, 9, 285293.
  • Ebling, F.J.G. & Randall, V.A. (1985) Hormonal actions on hair follicles & associated glands. In Methods in Skin Research (ed. D.Skerrow & C. J.Skerrow), pp. 297327. John Wiley.
  • Ebling, F.J.G., Randall, V.A. & Sawers, R.S. (1984) Interrelationships between body hair growth, serum excretion and endocrine parameters. Prostate, 5, 347348.
  • Ebling, F.J., Thomas, A.K., Cooke, I.D., Randall, V.A., Skinner, J. & Cawood, M. (1977) Effect of cyproterone acetate on hair growth, sebaceous secretion and endocrine parameters in a hirsute subject. British Journal of Dermatology, 97, 371381.
  • Eckert, J. Church, R.E., Ebling, F.J. & Munro, D.S. (1967) Hair loss in women. British Journal of Dermatology, 79, 543548.
  • Ewing, J.A. & Rouse, B.A. (1978) Hirsutism, race & testosterone levels: comparison of East Asians and Euro-Americans. Human Biology, 50, 209215.
  • Ferriman, D. & Gallwey, J.D. (1961) Clinical assessment of body hair growth in women. Journal of Clinical Endocrinology and Metabolism, 21, 14401447.
  • Franks, S. (1989) Polycystic ovary syndrome: a changing perspective (review). Clinical Endocrinology, 31, 87120.
  • Gambrell, R.D. (1987) Hormonal therapy. In The Cause and Management of Hirsutism (ed. R. B.Greenblatt, V. B.Mahesh & R. D.Gambrell), Parthenon Publishing Group, Carnforth , UK .
  • Geschwind, I.I. (1966) Change in hair colour in mice induced by injection of a-MSH. Endocrinology, 79, 11651167.
  • Goodhart, C.B. (1960) The evolutionary significance of human hair patterns and skin colouring. Advancement of Science, 17, 5358.
  • Greenblatt, R.B. & Gambrell, R.D. (1987) The ovary as a source of androgens A. The polycystic ovary B. Masculinising ovarian tumours. In The Cause & Management of Hirsutism (ed. R. B.Greenblatt, V. B.Mahesh & R. D.Gambrell), pp. 8397. Parthenon Publishing Group, Carnforth , UK .
  • Greenblatt, R.B., Mahesh, V.B. & Gambrell, R.D. (1987) The Cause and Management of Hirsutism. Parthenon Publishing Group, Carnforth , UK .
  • Griffin, J.E. & Wilson, J.D. (1989) The resistance syndromes: 5α- reductase deficiency, testicular feminisation and related disorders. In The Metabolic Basis of Inherited Disease (ed. C. R.Scriver, A. L.Baudot, W. S.Sly & D.Valle), pp. 19191944. McGraw-Hill, New York .
  • Griffins, K., Davies, P., Eaton, C.L., Harper, M.E., Peeling, W.B., Turkes, A.O., Turkes, A., Wilson, D.W. & Pierrepoint, G.G. (1987) Cancer of the prostate; endocrine factors. In Oxford Reviews of Reproductive Biology, Volume 9 (ed J. R.Clarke), pp. 192259. Oxford University Press, Oxford .
  • Hamada, K., Thornton, M.J., Laing, I., Messenger, A.G. & Randall, V.A. (1993) Uptake and metabolism of testosterone by dermal papilla cells cultured from pubic and axillary hair follicles. Journal of Investigative Dermatology (submitted).
  • Hamilton, J.B. (1942) Male hormone stimulation is a prerequisite and an incitant in common baldness. American Journal of Anatomy, 71, 451480.
  • Hamilton, J.B. (1946) A secondary sexual character that develops in men but not in women upon aging of an organ present in both sexes. Anatomical Record, 94, 466467.
  • Hamilton, J.B. (1951a) Quantitative measurement of a secondary sex character & axillary hair. Annals of the New York Academy of Science, 53, 585599.
  • Hamilton, J.B. (1951b) Patterned loss of hair in man; types and incidence. Annals of the New York Academy of Science, 53, 708728.
  • Hamilton, J.B. (1958) Age, sex and genetic factors in the regulation of hair growth in man: a comparison of Caucasian & Japanese populations. In The Biology of Hair Growth (ed. W.Montagna & R. A.Ellis) pp. 399433, Academic Press, New York .
  • Hamilton, J.B. (1960) Effect of castration in adolescent and young adult males upon further changes in the proportions of bare and hairy scalp. Journal of Clinical Endocrinology and Metabolism, 20, 13091318.
  • Hammerstein, J. (1987) Cyproterone acetate–the European experience. In The Cause and Management of Hirsutism (ed. R. B.Greenblatt, V. B.Mahesh & R. D.Gambrell), pp. 147159. Parthenon Publishing Group, Carnforth , UK .
  • Hart, J.S. (1956) Seasonal changes in insulation of the fur. Canadian Journal of Zoology, 34, 5357.
  • Hashimoto, K. (1988) The structure of human hair. Clinics in Dermatology, 6 (4), 721.
  • Hashimoto, K. & Shibizaki, S. (1976) Ultrastructural study on differentiation and function of hair. In Biology and Disease of the Hair (ed. K.Kobari & W.Montagna), pp. 2357. University Park Press, Tokyo , Baltimore .
  • Hibberts, N.A. & Randall, V.A. (1993) Dermal papilla cells from human balding scalp hair follicles contain higher levels of androgen receptors than those from non-balding scalp. Journal of Endocrinology, 137(Suppl.), 55.
  • Holbrooke, K.A. & Minami, S.I. (1991) Hair follicle embryogenesis in the human. Characterisation of events in vivo and in vitro. Annals of the New York Academy of Sciences, 642, 167196.
  • Hughes, I.A. & Evans, B.A.J. (1988) The fibroblast as a model for androgen resistant states. Clinical Endocrinolgy, 28, 565579.
  • Ibrahim, L. & Wright, E.A. (1982) A quantitative study of hair growth using mouse and rat vibrissal follicles. I Dermal papilla volume determines hair volume. Journal of Embryology and Experimental Morphology, 72, 209224.
  • Imperato-McGinley, J., Gautier, T., Cai, L., Yee, B., Epstein, J. & Pochi, P. (1993) The androgen control of sebum production. Studies of subjects with dihydrotestostcrone deficiency and complete androgen insensibility. Journal of Clinical Endocrinology and Metabolism, 76, 524528.
  • Imperato-McGinley, J., Peterson, R.E. & Gauter, T. (1984) Primary and secondary 5α-reductase deficiency. In Sexual Differentiation: Basic and Clinical Aspects (ed. M.Serio, M.Motta, M.Zanisi, & L.Martini), pp. 223232 Raven Press, New York .
  • Itami, S., Kurata, S. & Takay Asu, S. (1990) 5α-reductase activity in cultured human dermal papilla cells from beard compared with reticular dermal fibroblasts. Journal of Investigative Dermatology, 94, 150152.
  • Itami, S., Kurata, S., Sonoda, T. & Takayasu, S. (1991) Mechanism of action of androgens in dermal papilla cells. Annals of the New York Academy of Sciences, 642, 385395.
  • Jackson, D., Church, R.E. & Ebling, F.J. (1972) Hair diameter in female baldness. British Journal of Dermatology, 87, 361367.
  • Jahoda, C.A.B., Home, K.A. & Oliver, R.F. (1984) Induction of hair growth by implantation of cultured dermal papilla cells. Nature, 311, 560562.
  • James, V.H.T. & Andre, C.M. (1974) Androgen metabolism in the human female. In Biochemistry in Women: Clinical Concepts (ed. A. S.Curry & J. V.Hewitt), pp. 2329. CRC Press, Boca Raton .
  • Jeffcoate, W. (1993) The treatment of women with hirsutism. Clinical Endocrinology, 39, 143150.
  • Jenkins, J.S. & Ash, S. (1973) The metabolism of testosterone by human skin in disorders of hair growth. Journal of Endocrinology, 59, 345351.
  • Johnson, E. (1958) Quantitative studies of hair growth in the albino rat. I Normal males and females. Journal of Endocrinology, 16, 337350.
  • Johnson, E. (1977) Seasonal changes in the skin of mammals. Symposia of the Zoological Society of London, 39, 373404.
  • Johnson, E. & Ebling, F.J.G. (1964) The effect of plucking hairs during different phases of the follicular cycle. Journal of Embroyology and Experimental Morphology, 12, 465474.
  • Karpas, A.E. (1987) The adrenal as a source of androgens. In The Cause and Management of Hirsutism (ed. R. B.Greenblatt, V. B.Mahesh & R. D.Gambrell, pp. 99115. Parthenon Publishing Group, Carnforth , UK .
  • Kirschner, M.A. & Bardin, C.W. (1972) Androgen production in normal & virilised women. Metabolism, 21, 667688.
  • Kirschner, M.A., Zucker, I.R. & Jespersen, D.L. (1976) Ovarian and adrenal vein catherization studies in women with idiopathic hirsutism. In The Endocrine Function of the Human Ovary (ed. V. H. T.James, M.Serio & G.Gusti), pp. 443456. Academic Press, London .
  • Kligman, A.M. (1959) The human hair cycle. Journal of Investigative Dermatology, 33, 307316.
  • Kligman, A.M. (1961) Pathologic dynamics of human hair loss. I Telogen effluvium. Archives of Dermatology, 83, 175198.
  • Kligman, A.M. (1988) The comparative hisopathology of male-pattern baldness and senescent baldness. Clinics in Dermatology, 6 (4), 108118.
  • Kuttenn, F. & Mauvais-Jarvis, P. (1975) Testosterone 5a-reduction in the skin of normal subjects and of patients with abnormal sex development. Acta Endocrinologica (Copenh.), 79, 164–176.
  • Laznitzki, I., Takeda, H. & Mizuno, T. (1989) Autoradiographic studies of androgen-binding sites in human benign prostatic hyperplasia in vitro. Journal of Endocrinology, 120, 167170.
  • Leshin, M. & Wilson, J. (1981) Mechanisms of androgen-mediated hair growth. In Hair Research (ed. C. E.Orfanos, W.Montagna & G.Stuttgen), pp. 205209. Springer-Verlag, Berlin .
  • Ludwig, E. (1977) Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex. British Journal of Dermatology, 97, 247254.
  • Lynfield, Y.L. (1960) Effect of pregnancy on the human hair cycle. Journal of Investigative Dermatology, 35, 323327.
  • Mainwaring, W.I.P. (1977) The Mechanism of Action of Androgens. Monograpsh on Endocrinology. Volume 10. Springer-Verlag, Berlin .
  • Marshall, W.A. & Tanner, J.M. (1969) Variations in pattern of pubertal change in girls. Archives of Disease in Children, 44, 291303.
  • Marshall, W.A. & Tanner, J.M. (1970) Variations in the pattern of pubertal changes in boys. Archives of Disease in Children, 45, 1323.
  • Maudelonde, T.M., Rosenfield, R.L., Schuler, C.F. & Schwartz, S.A. (1986) Studies of androgen metabolism & action in cultured hair and skin cells. Journal of Steroid Biochemistry, 24, 10531060.
  • Mauvas-Jarvis, P., Charransol, G. & Bobas-Masson, F. (1973). Simultaneous determination of urinary androsteredoil & testosterone as an evaluation of human androgenicity. Journal of Clinical Endocrinology and Metabolism, 36, 452459.
  • Messenger, A.G. (1984) The culture of dermal papilla cells from human hair follicles. British Journal of Dermatology, 110, 685689.
  • Messenger, A.G., Elliott, K., Randall, V.A. & Temple, A. (1991) Dermal papillae of human hair follicles express interstitial collagens and basement membrane components in vivo and in vitro. Journal of Investigative Dermatology, 96, 9397.
  • Lesko, S.M., Rosenberg, L. & Shapiro, S. (1993) A case-control study of baldness in relation to myocardial infarction in men. Journal of the American Medical Association, 269, 9981003.
  • Lincoln, G.A. (1971) The seasonal reproductive changes in the red deer stag (Cervus elaphus). Journal of Zoology, 163, 105123.
  • Miller, J.A., Darley, C.R. Karkavitsas, K., Kirby, J.D. & Munro, D.D. (1982) Low sex hormone binding globulin levels in young women with diffuse hair loss. British Journal of Dermatology, 106, 331336.
  • Moerman, D.E. (1988) The meaning of baldness and implications for treatment. Clinics in Dermatology, 6, 8992.
  • Montagna, W., Chase, H.B., Malone, J.B. & Melaragno, H.P. (1952). Cyclic changes in polysaccharides of the papilla of the hair follicle. Quarterly Journal of the Microscopical Society, 93, 241245.
  • Montagna, W. & Van Scott, E.J. (1958) The anatomy of the hair follicle. In The Biology of Hair Growth (ed W.Montagna & R. A.Ellis), pp. 3964. Academic Press, New York .
  • Montagu, A. (1962) The functions of Man's distribution of hair. Journal of American Medical Association, 182, 281282.
  • Montgagu, A. (1964) National selection and man's relative hairlessness. Journal of the American Medical Association, 187, 356362.
  • Morgan, E. (1972) The Descent of Woman. Souvenir Press, London .
  • Morris, D. (1967) The Naked Ape. Jonathan Cape Ltd., Great Britain .
  • Norwood, O.T. (1975) Male pattern baldness: classification and incidence. Southern Medical Journal, 68, 13591365.
  • Oka, T. & Yoshimura, M. (1986) Paracrine regulation of mammary gland growth. In Paracrine Control. Clinics in Endocrinology, Volume 15 (ed P.Franchimont), pp. 7999. Saunders, London .
  • Oliver, R.F. & Jahoda, C.A.B. (1988) Dermal-epidermal interactions. Clinics in Dermatology, 6, 7482.
  • Oliver, R.F. & Jahoda, C.A.B. (1989) The dermal papilla and maintenance of hair growth. In The Biology of Wood and Hair (ed. G. E.Rogers, P. R.Reis, K. A.Ward & R. C.Marshall), pp. 5167. Chapman & Hall, London .
  • O'Malley, B.W. (1990) The steroid receptor superfamily: more excitement predicted for the future. Molecular Endocrinology, 4, 363369.
  • Orentreich, N. (1969) Scalp hair replacement in man. In Advances in Biology of Skin, Volume 9. Hair Growth (ed. W.Montagna & R. L.Dobson), pp. 99108. Pergamon Press, Oxford .
  • Orentreich, N. & Durr, N.P. (1982) Biology of scalp hair growth. Clinics in Plastic Surgery, 9, 197205.
  • Parker, M.G. (ed) (1991) Nuclear Hormone Receptors, Molecular Mechanisms, Cellular Functions, Clinical Abnormalities. Academic Press Ltd., London .
  • Parker, M.G. (ed) (1992) Growth regulation by nuclear hormone receptors. Cancer Surveys, Volume 14. Cold Spring Harbour Laboratory Press.
  • Patzer, G.L. (1988) Psychologic & sociologic dimensions of hair: an aspect of the physical attractiveness phenomenon. Clinics in Dermatology, 6, 93101.
  • Pecoraro, V., Astore, I. & Barman, J.M. (1968). The pre-natal and post-natal hair cycles in man. In Biopalhology of Pattern Alopecia (ed. A.Baccaredda-Boy, G.Moretti & J. R.Frey), pp. 2938. Karger, Basel .
  • Peereboom-Wynia, J.D.R., Van Der Willigen, A.H., Stolz, E. & Van Joost, T.H. (1989) The effect of cyproterone acetate on hair roots and hair shaft diameter in androgenetic alopecia in females. In Trends in Human Hair Growth and Alopecia Research (ed. D.VanNeste, J. M.Lachapelle & J. L.Antoine), pp. 207213. Kluwer Academic Publishers, Dordrecht .
  • Pinkus, H. (1958) Embryology of hair. In The Biology of Hair Growth (ed W.Montagna & R. A.Ellis), pp. 132. Academic Press, New York .
  • Pitts, R.L. (1987) Serum elevation of dehydroepiandrosterone sulphate associated with male pattern baldness in young men. Journal of American Academy of Dermatology, 16, 571573.
  • Price, V.H. (1988) Androgenetic alopecia and hair growth promotion state of the art: present and future. Clinics in Dermatology, 6, 21827.
  • Randall, V.A. (1994a) The role of 5α-reductase in health and disease. In Hormone-Nuclear Receptor Interactions in Health and Disease (ed. M.Sheppard & P.Stewart) Baillieres Clinical Endocrinology and Metabolism (in press).
  • Randall, V.A. (1994b) The mechanism of action of androgens in the human hair follicle. Proceedings of 1st Terra Symposium: Androgens & Antiandrogens (in press).
  • Randall, V.A. & Ebling, F.J.B. (1982) Is the metabolism of testosterone to 5α-dihydrotestosterone required for androgen action in the skin. British Journal of Dermatology, 107 (Suppl. 23), 4753.
  • Randall, V.A. & Ebling, F.J.G. (1991) Seasonal changes in human hair growth. British Journal of Dermatology, 124, 146151.
  • Randall, V.A., Ebling, F.J.G. & Hargreaves, G. (1982) In-vivo uptake and metabolism of testosterone by the skin and other tissues of the rat. Journal of Endocrinology, 93, 253266.
  • Randall, V.A., Ebling, F.J.G. & Sawers, R.S. (1984) Skin & endocrine changes during treatment with the antiandrogen, cyproterone acetate, and oestrogen. Prostate, 5, 348.
  • Randall, V.A., Thornton, M.J., Hamada, K., Redfern, C.P.F., Nutbrown, M., Ebling, F.J.G. & Messenger, A.G. (1991) Androgens and the hair follicle: cultured human dermal papilla cells as a model system. Annals of the New York Academy of Sciences, 642, 355375.
  • Randall, V.A., Thornton, M.J. & Messenger, A.G. (1992a) Cultured dermal papilla cells from androgen-dependent human follicles (e.g. beard) contain more androgen receptors then those from non-balding areas. Journal of Endocrinology, 133, 141147.
  • Randall, V.A., Thornton, M. J., Hamada, K. & Messenger, A.G. (1992b) Mechanism of androgen action in cultured dermal papilla cells derived from human hair follicles with varying responses to androgens in vivo. Journal of Investigative Dermatology, 98, 86S91S.
  • Randall, V.A., Thornton, M.J. & Messenger, A.G. (1992c) Androgens stimulate the secretion of mitogenic substance(s) by dermal papilla cells cultured from beard but not scalp follicles. British Journal of Dermatology, 125, 485.
  • Randall, V.A., Thornton, M.J., Messenger, A.G., Hibberts, N.A., Loudon, A.S.I. & Brinklow, B.R. (1993) Hormones and hair growth: variations in androgen receptor content of dermal papilla cells cultured from human & red deer (Cervus elaphus) hair follicles. Journal of Investigative Dermatology, 101, 11451205.
  • Read. G.F., Harper, M.E., Peeling, N.B. & Griffiths, K. (1981) Changes in male salivary testosterone concentration with age. International Journal of Andrology, 4, 623627.
  • Redmond, G.P. & Bergfield, W.F. (1990) Treatment of androgenetic disorders in women: acne, hirsutism and alopecia. Cleveland Clinic Journal of Medicine, 57, 482432.
  • Reingold, S.B. & Rosenfield, R.L. (1987) The relationship of mild hirsutism or acne in women to androgens. Archives of Dermatology, 123, 209212.
  • Reinberg, A., Lagoguey, M., Chauffourinier, J.M. & Cesselin, F. (1975) Circannual and circadian rhythms in plasma testosterone in five healthy young Parisian males. Acta Endocrinologica, 80, 732743.
  • Reynolds, E.L. (1951) The appearance of adult patterns of body hair in man. Annals of the New York Academy of Sciences, 53, 576584.
  • Reynolds, A.J. & Jahoda, C.A.B. (1991) Inductive properties of hair follicle cells. Annals of the New York Academy of Sciences, 642, 226242.
  • Reynolds, A.J. & Jahoda, C.A.B. (1992) Cultured dermal papilla cells induce follicle formation and hair growth by transdifferentiation of an adult epidermis. Development 115, 587593.
  • Rittmaster, R.S. (1988) Topical antiandrogens in the treatment of male-pattern baldness. Clinics in Dermatology, 6, 1228.
  • Roenigk, H.H.J.R., Pepper, E. & Kuruvilla, S. (1987) Topical minoxidil therapy for hereditary male pattern alopecia. Cutis, 39, 337342.
  • Rook, A.Dawber, R. (eds) (1991) Diseases of the Hair and Scalp. Second edition. Blackwell Scientific Publications, Oxford .
  • Rosenfield, R.L. (1981) Plasma testosterone binding globulin and indexes of the concentration of unbound androgens in normal and hirsute subjects. Journal of Clinical Endocrinology and Metabolism, 32, 717728.
  • Rust, C.C. (1965) Hormonal control of pelage cycles in the short-tailed weasel. General and Comparative Endocrinology, 5, 222231.
  • Ruutiainen, K., Erkkola, R., Kairiola, H.L., Santti, R. & Irjala, K. (1985) The grade of hirsutism correlated to serum androgens and hormonal indices. Acta Obstetrica Gynaecologica Scandinavia, 64, 629633.
  • Ruutiainen, K., Sannika, E., Santti, R., Erkkola, R. & Adlercreutz, H. (1987) Salivary testosterone in hirsutism: correlations with serum testosterone and the degree of hair growth. Journal of Clinical Endocrinology and Metabolism, 64, 10151020.
  • Saitoh, M. & Sakamoto, M. (1970) Human hair cycle. Journal of Investigative Dermatology, 54, 6581.
  • Sawers, R.A., Randall, V.A. & Iqbal, M.J. (1982) Studies on the clinical and endocrine aspects of antiandrogens. In Androgens and Antiandrogen Therapy. Current Topics in Endocrinology. Volume 1 (ed S. L.Jeffcoate), pp. 145168. John Wiley, Chichester .
  • Schweikert, H. & Wilson, J.D. (1974) Regulation of human hair growth by steroid hormones. I Testosterone metabolism in isolated hair. Journal of Clinical Endocrinology and Metabolism, 40, 413417.
  • Seago, S.V. & Ebling, F.J.G. (1985) The hair cycle on the human thigh and upper arm. British Journal of Dermatology, 113, 916.
  • Serafini, P., Ablan, F. & Lobo, R.A. (1985). 5α-reductase activity in the genital skin of hirsute women. Journal of Clinical Endocrinology and Metabolism, 60, 349355.
  • Severaid, J.H.S. (1945) Pelage changes in the snowshoe hare, Lepus americanus. Journal of Mammalology, 26, 4163.
  • Setty, L.R. (1970) Hair patterns of the scalp of white and negro males. American Journal of Physical Anthropology, 33, 4955.
  • Sims, R.T. (1967) Hair growth in kwashiorkor. Archives of Disease in Children, 42, 397400.
  • Smals, A.G.H., Kloppenberg, P.W.C. & Benraad, T.H.J. (1976) Circannual cycle in plasma testosterone levels in man. Journal of Clinical Endocrinology and Metabolism, 42, 979982.
  • Smith, A.J., Mondain-Monval, M., Berg, K.A., Simon, P., Fosberg, M., Clausen, O.P.F., Hansen, T., Moller, O.M. & Scholler, R. (1987a) Effects of melatonin implantations on spermatogenesis, the moulting cycle and plasma concentrations of melatonin, LH, prolactin and testosterone in the male blue fox (Alopex lagopus). Journal of Reproduction and Fertility, 79, 379390.
  • Smith, A.J., Mondain-Monval, M., Simon, P., Andersen Berg, K., Clausen, O.P.F., Hofmo, P.O. & Scholler, R. (1987b) Preliminary studies of the effects of bomocriptine on testicular regression and the spring moult in a seasonal breeder, the male blue fox (Alopex lagopus). Journal of Reproduction and Fertility, 81, 517524.
  • Stumpf, W.E. & Sar, M. (1976) Autoradio graphic localisation of estrogen, androgen, progestin and glucocorticosteroid in ‘target tissues' and ‘non-target tissues'. In Modern Pharmacology-Toxicology, 8, Mechanism of Action of Steroid Hormones (ed J.Pasqualini), pp. 4148, Marcel Dekker, New York .
  • Thomas, J.P. & Oake, R.J. (1974) Androgen metabolism in the skin of hirsute women. Journal of Clinical Endocrinology and Metabolism, 38, 1922.
  • Thornton, M.J., Laing, I., Hamada, K., Messenger, A.G. & Randall, V.A. (1993) Differences in testosterone metabolism by beard and scalp hair follicle dermal papilla cells. Clinical Endocrinology, 39, 633639.
  • Thornton, M.J., Messenger, A.G., Elliott, K. & Randall, V.A. (1991) Effect of androgens on the growth of cultured human dermal papilla cells derived from beard and scalp hair follicles. Journal of Investigative Dermatology, 97, 345348.
  • Uno, H. (1987) Stump-tailed macaques as a model of male pattern baldness. In Models in Dermatology. Volume 3 (ed. H. I.Maibach & N. J.Lowe), pp. 159169. Karger, Basel .
  • Van Scott, E.J. & Ekel, T.M. (1958) Geometric relationships between the matrix of the hair bulb and its dermal papilla in normal and alopecic scalp. Journal of Investigative Dermatology, 301, 281287.
  • Vaughan, T.A. (1986) Mammalology, Third edition. Saunders College Publishing, New York .
  • Venning, V.A. & Dawber, R. (1988) Patterned androgenic alopecia. Journal of the American Academy of Dermatology, 18, 10731077.
  • Vermeulen, A., Stoica, T. & Verdonck, L. (1971) The apparent free testosterone concentration, an index of androgenicity. Journal of Clinical Endocrinology and Metabolism, 33, 759767.
  • Weinstien, G.D. & Mooney, K.M. (1980) Cell proliferation kinetics in the human hair root. Journal of Investigative Dermatology, 74, 4346.
  • Winter, J.S.D. & Faiman, C. (1972) Pituitary-gonadal relations in male children and adolescents. Paediatric Research, 6, 125135.
  • Winter, J.S.D. & Faiman, C. (1973) Pituitary-gonadal relations in female children and adolescents. Paediatric Research, 7, 948953.
  • Wojnarowska, F.T. (1991) Psychological factors and disorders of the hair. In Diseases of the Hair and Scalp (ed. A.Rook & R.Dawber), pp. 458464. Blackwell Scientific Publications, Oxford .
  • Young, J.Z. (1981) The Life of the Vertebrates. Third edition. Oxford University Press, Oxford .
  • Young, R.D. (1980) Morphological and ultrastructural aspects of the dermal papilla during the growth cycle of the vitrissal follicle in the rat. Journal of Anatomy, 131, 355365.
  • Zachmann, M. & Prader, A. (1970) Anabolic and androgenetic effect of testosterone in sexually immature boys and its dependency on G. H. Journal of Clinical Endocrinology and Metabolism, 30, 8595.
  • Zachmann, M., Aynsley-Green, A. & Prader, A. (1976) Interrelations of the effects of growth hormone and testosterone in hypopituitarism. In Growth Hormone and Relatged Peptides (ed. A.Pecile & E. E.Muller), pp. 286296. Excerpta Medico, Amsterdam and Oxford.
  • Zins, G. R. (1988) History of minoxidil. Clinics in Dermatology, 6, 132143.