Treatment of hypopharyngeal carcinoma: analysis of nationwide study in the Netherlands over a 10-year period
Version of Record online: 3 MAR 2005
Volume 30, Issue 1, pages 52–57, February 2005
How to Cite
Sewnaik, A., Hoorweg, J.J., Knegt, P.P., Wieringa, M.H., van der Beek, J.M.H. and Kerrebijn, J.D.F. (2005), Treatment of hypopharyngeal carcinoma: analysis of nationwide study in the Netherlands over a 10-year period. Clinical Otolaryngology, 30: 52–57. doi: 10.1111/j.1365-2273.2004.00913.x
- Issue online: 3 MAR 2005
- Version of Record online: 3 MAR 2005
- Accepted 26 January 2004
- hypopharyngeal carcinoma;
Objective: To analyse different treatment strategies and treatment results of hypopharyngeal carcinoma in the Netherlands.
Design: Retrospective study.
Setting: Eight head and neck centres in the Netherlands.
Participants: A total of 893 patients were treated between 1985 and 1994. Patients were mostly treated with radiotherapy alone, combined surgery and radiotherapy and surgery alone.
Results: The 5-year survival for the whole group was 26%. The 5-year survival for patients treated with curative intention was 32% and treated with palliative intention was 5%. The 5-year disease-free survival after radiotherapy alone was 37%, after surgery alone 41% and after combined therapy 47%. The role of chemotherapy could not be investigated because of a small number of patients treated with chemotherapy in this period.
Conclusion: Combined therapy with surgery and radiotherapy has a better survival for patients with a hypopharyngeal carcinoma in comparison with radiotherapy alone. The N-stage is more important for the prognosis than the T-stage.