Membership of the GRIPS Group is provided in the Acknowledgments.
Strengthening the reporting of genetic risk prediction studies: the GRIPS statement
Article first published online: 15 MAR 2011
© 2011 The Authors. European Journal of Clinical Investigation © 2011 Stichting European Society for Clinical Investigation Journal Foundation
European Journal of Clinical Investigation
Volume 41, Issue 9, pages 1004–1009, September 2011
How to Cite
Janssens, A. C. J. W., Ioannidis, J. P. A., van Duijn, C. M., Little, J., Khoury, M. J. and for the GRIPS Group (2011), Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. European Journal of Clinical Investigation, 41: 1004–1009. doi: 10.1111/j.1365-2362.2011.02494.x
This article is being simultaneously published in 2011 in PLoS Medicine, Annals of Internal Medicine, BMJ, Circulation: Cardiovascular Genetics, European Journal of Clinical Investigation, European Journal of Epidemiology, European Journal of Human Genetics, Genetics in Medicine, Genome Medicine, and Journal of Clinical Epidemiology. Reproduced by permission of the authors.
- Issue published online: 3 AUG 2011
- Article first published online: 15 MAR 2011
- Received 24 January 2011; accepted 24 January 2011
Eur J Clin Invest 2011; 41 (9): 1004–1009
- •The rapid and continuing progress in gene discovery for complex diseases is fuelling interest in the potential application of genetic risk models for clinical and public health practice.
- •The number of studies assessing the predictive ability is steadily increasing, but the quality and completeness of reporting vary.
- •A multidisciplinary workshop sponsored by the Human Genome Epidemiology Network developed a checklist of 25 items recommended for strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS), building on the principles established by prior reporting guidelines.
- •These recommendations aim to enhance the transparency of study reporting and thereby to improve the synthesis and application of information from multiple studies that might differ in design, conduct or analysis.
- •A detailed Explanation and Elaboration document is published as an accompanying article .