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Figure S1 Zygotic expression of Sall4 in embryogenesis.

Figure S2 Anal abnormality and exencephaly in Sall4 heterozygous mice.

Figure S3 Early embryonic lethality of Sall4-null mutants.

Figure S4 The characterization of ES cells established from Sall4-null blastocysts.

Figure S5 The protein levels of Sall4 depletion with using Sall4 shRNA in ectopic expression.

Figure S6 The characterization of human iPS cells generated with 3F + SALL4 from human fibroblasts.

Figure S7 The expression levels of the endogenous Sall4 mRNA in several human fibroblasts.

Table S1 Primers and oligonucleotides used in this study

Table S2 HDF lines

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