William Hewson and the blood which issued last but clotted first: the beginning of the story of desmopressin in haemophilia and vWD


  • G. I. C. Ingram M.D., F.R.C.P., F.R.C.Path, F.L.S.,

    1. Formerly Professor of Experimental Haematology, St Thomas's Hospital Medical School, London, SE1; 42, Burford Lodge, Pegasus Grange, Whitehouse Road, Oxford OX1 4QG.*
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  • P. M. Mannucci M.D.

    1. Professor of Medicine, Director, Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre (WHO Collaborating Centre), IRCCS Maggiore Hospital and University of Milan, Italy.
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  • Sadly, we are left with no details of the ingenious coagulometers which Hayem invented, and which, his footnote of 1889 [14] tells us, he was forced to abandon in favour of un procédé extrêmement simple.